Cancers Journal (MDPI) Guest Editor, Raushan Kurmasheva, PhD, invites relevant research work for publication.
February 24, 2023Raushan Kurmasheva (Guest Editor) invites relevant research work for publication in a new Special Issue of the Cancers Journal (MDPI) titled “Pediatric Cancer: From Molecular Targets to Effective Therapies.” Please, find more information here:https://w …
Nature Communications: DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation (Sung Lab)
February 7, 2023Youngho Kwon, Heike Rösner, Weixing Zhao, Platon Selemenakis, Zhuoling He, Ajinkya S. Kawale, Jeffrey N. Katz, Cody M. Rogers, Francisco E. Neal, Aida Badamchi Shabestari, Valdemaras Petrosius, Akhilesh K. Singh, Marina Z. Joel, Lucy Lu, Stephen P. Hol …
2023 Spatial Transcriptome Pilot Projects
February 6, 2023Overview The Greehey Children’s Cancer Research Institute, Genomic Sequencing Facility, expects to support four Spatial Transcriptome pilot projects (two human and two mouse Visium slides, one per proposal). It is crucial to identify pilot grants that …
Structure: Order and disorder bound together in SARS-CoV-2 Nsp1 suppress host translation (Libich Lab)
February 6, 2023David S Libich 1, Antoine Baudin 2 Abstract In this issue of Structure, Wang et al. investigate the interplay between folded and disordered regions of the SARS-CoV-2 non-structural protein 1 (Nsp1) that promotes the suppression of host protein translat …
Neuro-Oncology: Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double strand break repair and augments efficacy of temozolomide in glioblastoma (Chen, Lao)
January 23, 2023Salvador Alejo, Bridgitte E Palacios, Prabhakar Pitta Venkata, Yi He, Wenjing Li, Jessica D Johnson, Chen Yihong, Sridharan Jayamohan, Uday P Pratap, Kyra Clarke, Yi Zou, Yingli Lv, Korri Weldon, Suryavathi Viswanadhapalli, Zhao Lai, Zhenqing Ye, Yidon …
Precision Oncology News: Lantern Pharma Preparing IND for Synthetic Lethality Program With FDA Feedback
January 18, 2023Jan 17, 2023 | staff reporter NEW YORK – Lantern Pharma on Tuesday said it received feedback from the US Food and Drug Administration that it will use to submit an investigational new drug application for LP-184. The company furthe …
Star Protocols: Protocol to benchmark gene expression signature scoring techniques for single-cell RNA sequencing data in cancer (Zheng Lab)
January 4, 2023Nighat Noureen123 Xiaojing Wang12 Siyuan Zheng124 • Protocol for benchmarking signature scoring techniques in scRNAseq data analysis • Comparing single-cell and bulk-based approaches in sensitivity and specificity • Using down sampling to simulate the …
Molecular Cancer Theraputics: Sensitization to Ionizing Radiation by MEK Inhibition Is Dependent on SNAI2 in Fusion-Negative Rhabdomyosarcoma (Ignatius, Vaseva, Houghton Labs)
January 3, 2023Nicole R. Hensch, Kathryn Bondra, Long Wang, Prethish Sreenivas, Xiang R. Zhao, Paulomi Modi, Angelina V. Vaseva, Peter J. Houghton, Myron S. Ignatius Abstract In fusion-negative rhabdomyosarcoma (FN-RMS), a pediatric malignancy with skeletal muscle ch …
Genes & Cancer: Slit2 signaling stimulates Ewing sarcoma growth (Shiio Lab)
December 19, 2022Kruthi Suvarna1, Panneerselvam Jayabal1, Xiuye Ma1 and Yuzuru Shiio1,2,3 1 Greehey Children’s Cancer Research Institute, The University of Texas Health Science Center, San Antonio, TX 78229-3900, USA 2 Cancer Therapy and Research Center, The University …
Luiz Penalva, PhD to Receive Mike Hogg Fund Award
December 15, 2022Luiz O.F. Penalva, PhD to receive an award from the Mike Hogg Fund in support of his study, “Preventing Senescence Scape to Overcome Tumor Recurrence in Glioblastoma.” Learn more about Dr. Penalva’s research