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JCO Oncology Practice: Disparities in Cancer Genetic Testing and Variants of Uncertain Significance in the Hispanic Population of South Texas (Tomlinson Lab, Ignatius Lab)

May 12, 2022

Stephanie Soewito, BS, MS1; Rachel Wyatt, MS2; Emily Berenson, MS2; Natalie Poullard, MS, MA3; Shawn Gessay, MS2,3,4; Lindsey Mette, MS, MPH2,3,5; Elena Marin, CHW6; Kristin Shelby, BA6; Elise Alvarez, BA3; Byeong Yeob Choi, PhD7; Clarissa Aviles, MSHS …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Nature Communications: Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing (Sung)

April 27, 2022

Chaoyou Xue, Sameer J. Salunkhe, Nozomi Tomimatsu, Ajinkya S. Kawale, Youngho Kwon, Sandeep Burma, Patrick Sung & Eric C. Greene Nature Communications volume 13, Article number: 2248 (2022) Cite this article Abstract Bloom syndrome (BS) is associat …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Molecular Carcinogenesis: SIRT1 inhibition-induced senescence as a strategy to prevent prostate cancer progression (Chen, Lai)

April 25, 2022

Abstract Emerging evidence suggests an important role for SIRT1, a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase in cancer development, progression, and therapeutic resistance; making it a viable therapeutic target. Here, we examined th …


Oncogene: Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma (Vaseva)

April 25, 2022

Patience Odeniyide, Marielle E. Yohe, Kai Pollard, Angelina V. Vaseva,  Ana Calizo, Lindy Zhang, Fausto J. Rodriguez, John M. Gross, Amy N. Allen, Xiaolin Wan, Romel Somwar, Karisa C. Schreck, Linda Kessler, Jiawan Wang & Christine A. Pratilas Abst …


Gupta to Present at Cold Spring Harbor Meeting on Regulatory & Non-coding RNAs

April 24, 2022

Dr. Gupta’s virtual presentation at the Cold Spring Harbor meeting (May 17 – 21, 2022) is titled RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro virtual talk. Read More


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Clinical Cancer Research: The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models (Kurmasheva & Houghton)

April 22, 2022

Nathan M Kendsersky # 1 2, Jarrett Lindsay # 1 2, E Anders Kolb 3, Malcolm A Smith 4, Beverly A Teicher 4, Stephen W Erickson 5, Eric J Earley 5, Yael P Mosse 1, Daniel Martinez 6, Jennifer Pogoriler 2 6, Kateryna Krytska 1, Khushbu Patel 1 7, David Gr …


Non-Coding RNA: Current Status of Epitranscriptomic Marks Affecting lncRNA Structures and Functions (Bishop Lab)

April 22, 2022

by Henry E. Miller 1,2,3ORCID, Mirolyuba Ilieva 4, Alexander J. R. Bishop 1,2,5ORCID and Shizuka Uchida 4, Non-Coding RNA 2022, 8(2), 23; https://doi.org/10.3390/ncrna8020023 Received: 1 March 2022 / Revised: 21 March 2022 / Accepted: 25 March 2022 / P …


American Society for Biochemistry and Molecular Biology: Sung takes over at San Antonio cancer institute

April 18, 2022

Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Dr. Kurmasheva to be Awarded Helen Freeborn Kerr Charitable Foundation Grant

April 18, 2022

Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

BMC: SETDB1 interactions with PELP1 contributes to breast cancer endocrine therapy resistance (Lai, Chen, Rao)

April 11, 2022

Zexuan Liu, Junhao Liu, Behnam Ebrahimi, Uday P. Pratap, Yi He, Kristin A. Altwegg, Weiwei Tang, Xiaonan Li, Zhao Lai, Yidong Chen, Liangfang Shen, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Rajeshwar R. Tekmal, Manjeet K. Rao & Ratna K. Va …