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Yogesh Gupta Awarded, 5-year $3.0 million R01 NIH/NIAID Grant to Support His SARS-CoV-2 and RNA Methylation Work.

July 29, 2021

Dr. Yogesh Gupta was awarded a 5-year $3.0 million R01 NIH/NIAID (National Institute of Allergy and Infectious Diseases) grant to support his SARS-CoV-2 and RNA methylation work. ABSTRACT The massive global pandemic with high morbidity and mortality ma …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Science Advances: Regulation of telomere homeostasis and genomic stability in cancer by N6-adenosine methylation (m6A) (Rao & Zheng Labs)

July 29, 2021

View ORCID ProfileJi Hoon Lee1,†, View ORCID ProfileJuyeong Hong1,†, View ORCID ProfileZhao Zhang1,†, View ORCID ProfileBárbara de la Peña Avalos2,3, View ORCID ProfileCecilia J. Proietti4, View ORCID ProfileAgustina Roldán Deamicis4, View ORCID Profil …


Drs. Tomlinson and Kurmasheva to be Profiled in San Antonio Woman Magazine Article

July 23, 2021

Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Scientific Reports: A comprehensive meta-analysis and a case–control study give insights into genetic susceptibility of lung cancer and subgroups (Bishop Lab)

July 19, 2021

Debmalya Sengupta, Souradeep Banerjee, Pramiti Mukhopadhyay (Bishop Lab)  Ritabrata Mitra, Tamohan Chaudhuri, Abhijit Sarkar, Gautam Bhattacharjee, Somsubhra Nath, Susanta Roychoudhury, Samsiddhi Bhattacharjee & Mainak Sengupta Abstract Reports of …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

eLife Sciences: Loss of MGA repression mediated by an atypical polycomb complex promotes tumor progression and invasiveness (Shiio Lab)

July 9, 2021

    Haritha Mathsyaraja,  Jonathen Catchpole,  Brian Freie,  Emily Eastwood,  Ekaterina Babaeva,  Michael Geuenich,  Pei Feng Cheng,  Jessica Ayers,  Ming Yu,  Nan Wu,  Sitapriya Moorthi,  Kumud R Poudel,  Amanda Koehne,  William Grady,  A Mc …


Cell Reports: NELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growthNELL2-cdc42 signaling regulates BAF complexes and Ewing sarcoma cell growth (Shiio, Houghton)

July 8, 2021

Panneerselvam Jayabal1, Fuchun Zhou1, Xiufen Lei1, XiuyeMa1, Barron Blackman1, Susan T.Weintraub23, Peter J.Houghton134, YuzuruShiio1235 Highlights • The autocrine signaling mediated by NELL2 maintains Ewing sarcoma cell growth • NELL2 signaling inhibi …


Dr. Houghton Co-Authors MDPI paper, “Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells

July 2, 2021

Authored by: Jun Luo, Yoshinobu Odaka, Zhu Huang, Bing Cheng, Wang Liu, Lin Li, Chaowei Shang, Chao Zhang, Yang Wu, Yan Luo, Shengyong Yang, Peter J. Houghton, Xiaofeng Guo, Shile Huang Abstract Dihydroartemisinin (DHA), an anti-malarial drug, has been …


Nature Communications: Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase (Gupta)

June 29, 2021

Yogesh Gupta PhD Olga Rechkoblit, Robert E. Johnson, Yogesh K. Gupta, Louise Prakash, Satya Prakash & Aneel K. Aggarwal Abstract PrimPol is a human DNA polymerase-primase that localizes to mitochondria and nucleus and bypasses the major oxidative l …


Adam Kosti Successfully Defends PhD Dissertation (Penalva Lab)

June 21, 2021

Join us in congratulating Adam Kosti of the Penalva Lab for successfully defending his dissertation, “microRNA-Transcription Factor Networks in Gliomagenesis” last week. Mentor: Dr. Luiz Penalva Program: PhD in Integrated Biomedical Sciences Discipline …


Angelina Vaseva, PhD Presented 2021 Voelcker Pilot Award (Houghton Lab)

June 16, 2021

Angelina Vaseva, PhD Congratulations to Angelina Vaseva, PhD, research assistant professor at Greehey Children’s Cancer Research Institute and the Department of Molecular Medicine, on being presented a 2021 2021 Voelcker Pilot Award. Dr. Vaseva’s proje …