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Molecular Cancer Research: GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer (Chen)

October 27, 2021

Marieke Burleson, Janice J. Deng, Tai Qin, Thu Minh Duong, Yuqian Yan, Xiang Gu, Debodipta Das, Acarizia Easley, Michael A. Liss, P. Renee Yew, Roble Bedolla, Addanki Pratap Kumar, Tim Hui-Ming Huang, Yi Zou, Yidong Chen, Chun-Liang Chen, Haojie Huang, …


Free Radical Biology and Medicine: Thioredoxin reductase-1 levels are associated with NRF2 pathway activation and tumor recurrence in non-small cell lung cancer (Bishop Lab)

October 26, 2021

MarinaDelgoboa  Rosângela MayerGonçalvesag  Marco AntônioDelazerib  MarceloFalchettia  AlessandroZandonáb  RaquelNascimento das Nevesa  KarolineAlmeidaa  Adriane CristinaFagundesa  Daniel PensGelainc  João IsidroFracassod  Guilherme Baroni deMacêdod  L …


Yogesh Gupta PhD, to Receive UT Health SA “Rising Research Star” Award

October 25, 2021

Yogesh Gupta, PhD Assistant Professor Department of Biochemistry & Structural Biology​ Greehey Children’s Cancer Research Institute Last week, our very own Yogesh Gupta PhD, was recognized as one of the 2021 Joe R. and Teresa Lozano Long School of …


PIPETTE GAZETTE – Meet The Researcher: Aiola Stoja and her love for dogs, hiking and cancer research (Bishop Lab)

October 22, 2021

While Aiola Stoja Payne was volunteering as an emergency medical technician (EMT), she learned about a new substance that was just being implemented in emergency medicine. She was taught that this substance was a powder that you put directly on the wou …


JoVE: Paramagnetic Relaxation Enhancement for Detecting and Characterizing Self-Associations of Intrinsically Disordered Proteins (Libich Lab)

October 13, 2021

Courtney N. Johnson1, David S. Libich1 Abstract Intrinsically disordered proteins and intrinsically disordered regions within proteins make up a large and functionally significant part of the human proteome. The highly flexible nature of these sequence …


Frontiers in Molecular BioScience: Structural Characterization of the RNA-Binding Protein SERBP1 Reveals Intrinsic Disorder and Atypical RNA Binding Modes (Libich & Penalva labs)

October 13, 2021

Antoine Baudin, 1 , 2 , † Alma K. Moreno-Romero, 1 , 2 Xiaoping Xu, 1 , 2 Emily E. Selig, 1 , 2 , † Luiz O. F. Penalva, 1 , 3 and David S. Libich 1 , 2 ,* † Abstract RNA binding proteins (RBPs) are essential for critical biological processes such as tr …


Journal of Palliative Medicine: When a Tumor Becomes a Legacy: A Collection of Perspectives (Ignatius & Tomlinson Labs)

October 4, 2021

Amanda E. Lipsitt, Patricia K. DeForest, Andrea J. Canon, Andrea R. Gilbert, and Gail E. Tomlinson Introduction The following is a story in the form of a collection of personal perspectives from our medical team members who treated a young woman with o …


MDPI: Surfaceome Profiling of Rhabdomyosarcoma Reveals B7-H3 as a Mediator of Immune Evasion (Houghton)

September 28, 2021

Roxane R. Lavoie Patricio C. Gargollo Mohamed E. Ahmed Yohan Kim Emily Baer Doris A. Phelps Cristine M. Charlesworth Benjamin J. Madden Liguo Wang Peter J. Houghton John Cheville Haidong Dong Candace F. Granberg Fabrice Lucien Simple Summary Rhabdomyos …


Journal of Virology: MULTIPLEXED SIV-SPECIFIC PAIRED RNA-GUIDED CAS9 NICKASES INACTIVATE PROVIRAL DNA (Lai)

September 23, 2021

Authors: Lisa M Smith, Jason T. Ladner, Vida L. Hodara, Laura M. Parodi, R. Alan Harris, Jessica E. Callery, Zhao Lai, Yi Zou, Muthuswamy Raveedran, Jeffrey Rogers, and Luis D. Giavedoni Abstract Human and simian immunodeficiency virus infections estab …


Cambridge Core: Examining Access to Care in Clinical Genomic Research and Medicine: Experiences from the CSER Consortium (Tomlinson)

September 21, 2021

Amanda M. Gutierrez[Opens in a new windo Jill O. Robinson, Simon M. Outram, Hadley S. Smith, Stephanie A. Kraft, Katherine E. Donohue, Barbara B. Biesecker, Kyle B. Brothers, Flavia Chen, Benyam Hailu, Lucia A. Hindorff, Hannah Hoban, Rebecca L. Hsu, S …