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Childhood Cancer Awareness Month: THE SCIENCE BEHIND THE GOLD RIBBON: THE CHEN LAB🎗️

September 2, 2026

Cancer research generates an enormous amount of data. Hidden inside that data are clues that can help researchers better understand why childhood cancers develop, how they behave, and which treatments may work best. At the Greehey Children’s Cancer Res …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Nucleic Acids Research: Researchers Find a New Weak Spot in Cancer’s DNA Repair System (Olsen, Zhou, Sung Lab, Hromas)

September 1, 2026

Every time a cell divides, it has to copy billions of pieces of DNA. It is an incredibly complicated process, and mistakes or damage are inevitable. Healthy cells have several ways to fix those problems before they become dangerous. Cancer cells do, to …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Childhood Cancer Awareness Month: 🎗️THE SCIENCE BEHIND THE GOLD RIBBON: THE AUNE LAB

September 1, 2026

Gregory J. Aune, MD, PhD, Surviving childhood cancer is the goal. But survival can come with consequences that last a lifetime. At the Greehey Children’s Cancer Research Institute, the Aune Lab, led by Gregory J. Aune, MD, PhD, studies the long-term he …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

SAVE-THE-DATE: SATX Social Ride Presents the 3rd Gold Ribbon Ride

August 25, 2026

We’re kicking off Childhood Cancer Awareness Month with the SATX Social Ride 3rd Annual Gold Ribbon Ride, and we’d love to have you roll with us. Join SATX Social Ride and the Greehey Children’s Cancer Research Institute for a relaxed evening ride brin …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Cell Reports: EWSR1::FLI1 promotes neocentromere formation in Ewing sarcoma cells (Zheng, Sung Lab, Kitagawa Lab)

August 17, 2026

Risa Kitagawa1,2 ∙ Ediri E. Metitiri1,2 ∙ Bin Yu1,2 ∙ Changxian Shen1,2,6 ∙ Alexander J.R. Bishop1,3,5 ∙ Siyuan Zheng1,4 ∙ Peter J. Houghton1,2 ∙ Katsumi Kitagawa1,2,7 Send email to kitagawak@uthscsa.edu Highlights Summary Ewing sarcoma (EwS) is charac …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Nature Communications: HELZ-BRCA2 complex resolves R-loops to drive transcription-coupled homologous recombination (Wasmuth, Zheng, Sung Lab, Zhao)

August 12, 2026

Wenjing Li, Bo Wu, Boya Gao, Elizabeth M. Irvin, Arijit Ghosh, Lillian Eliaz, Yuxin Huang, Youngho Kwon, Clara M. Stiefel, Tram Thi Ngoc Nguyen, David Zhao, Humberto Javier Suarez, Tengyang Ni, Salvador Alejo, O’Taveon Fitzgerald, Xuemei Song, Sandip K …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Function: Constitutive mTORC1 Activation in Skeletal Muscle Increases Inflammation but is not Sufficient to Impair Glucose Tolerance (Lai Lab)

July 23, 2026

Erik D. Marchant, Hanna Kalenta, Sean P. Kilroe, Jacquelyn May, Wenjun Z. Martini, Korri S. Weldon, Zhao Lai, and Blake B. Rasmussen  Abstract Aberrant mechanistic target of rapamycin complex 1 (mTORC1) signaling in skeletal muscle has been implicated …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Nature Communications: Multifaceted roles of PDS5B in RAD51-dependent homology-directed DNA repair and replication fork protection (Sung Lab, Libich, Olsen, Wasmuth, Rao, et al)

July 22, 2026

Jeffrey N. Katz, Lorena Samentar, Qingming Fang, Jae-Hoon Ji, Wenjing Li, Qiongmei Gao, Sahiti Kuppa, Boya Gao, Cody M. Rogers, Hardeep Kaur, Aida Badamchi Shabestari, Arijit Dutta, Shahrez Syed, Miriam Tovar, Nozomi Tomimatsu, Bipasha Mukherjee, Eliza …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Nature Structural & Molecular Biology: CST complex promotes second-strand synthesis in break-induced replication (Sung Lab, Malkova, et al)

July 21, 2026

Pilendra Thakre, Jeff Wang, Liping Liu, Sameer Shah, Zhenxin Yan, Nhung Pham, Meng-Chia Tsai, Yuqin Zhao, Cody M. Rogers, Zhitong Feng, Hengyao Niu, Youngho Kwon, Xiaohua Wu, Anna Malkova, Patrick Sung & Grzegorz Ira Abstract Break-induced DNA repl …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Nature Communications: Break-induced replication forms long mutable single-strand DNA during meiosis (Malkova)

June 22, 2026

Thanks to advances in treatment, more than 85% of children diagnosed with cancer now survive into adulthood. However, many survivors face long-term health challenges caused by their cancer treatments, including heart disease, diabetes, high blood press …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.