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Greehey CCRI Archives

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“Singing in the Mud”, Message from the Dean

April 13, 2020

Former UT Chancellor, retired Admiral, and retired Navy Seal William H. McRaven wrote a story in the Washington Post that is worth sharing widely- “For a would-be Navy SEAL, Hell Week is the worst week of the toughest military training in the world. It …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Familial Cancer: Highly aggressive thoracic desmoid tumors in adolescent siblings with fatal outcomes in an FAP kindred: a need for increased vigilance and intervention in at-risk AYAs

April 13, 2020

Mohamed M. Gad, Anne-Marie Langevin, Aaron J. Sugalski & Gail E. Tomlinson Abstract Desmoid tumors are a manifestation of familial adenomatous polyposis (FAP), associated with mutation of the APC gene. Although considered benign tumors, desmoids ca …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Pipette Gazette: Unknown Pathogenic Agents: When Common Decency Is Better Than Nothing (Aune Lab)

April 6, 2020

Originally Published, Pipette Gazette: By: Brian Iskra, The pandemic of COVID-19 is a challenging situation for every member of society; we all have our role to play in mitigating the mortality caused by the infection. Medical professionals are at the …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

BMG Medical Genomics: Convolutional neural network models for cancer type prediction based on gene expression

April 3, 2020

Milad Mostavi, Yu-Chiao Chiu, Yufei Huang & Yidong Chen Abstract Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Through a predictive model, important cancer marker genes can be inferred. Several studies hav …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Pain Reports: Reliable approaches to extract high-integrity RNA from skin and other pertinent tissues used in pain research

March 27, 2020

Peter M LoCoco 1, Jacob T Boyd 1, Claudia M Espitia Olaya 2, Ashley R Furr 1, Dawn K Garcia 3, Korri S Weldon 3, Yi Zou 3, Erin Locke 1, Alejandro Tobon 4, Zhao Lai 3 5, Shivani B Ruparel 1, Nikita B Ruparel 1, Kenneth M Hargreaves 1 Abstract Introduct …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

KLRN: The Gene San Antonio | Dr. Gregory Aune

March 27, 2020

https://www.youtube.com/watch?v=nKvk6YL-MVg     Aune Lab    


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Katsumi Kitagawa, Pharm.D., PhD Awarded $1M NSF Grant

March 16, 2020

Overview: Centromeres are essential for chromosome segregation during mitosis. The kinetochore is the protein complex associated with the centromere. Dysfunction in centromeres causes chromosome instability and can result in aneuploidy. The overall goa …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

bioRxiv : Assessing the Heterogeneity of Cardiac Non-myocytes and the Effect of Cell Culture with Integrative Single Cell Analysis

March 4, 2020

Abstract Cardiac non-myocytes comprise a diverse and crucial cell population in the heart that plays dynamic roles in cardiac wound healing and growth. Non-myocytes broadly fall into four cell types: endothelium, fibroblasts, leukocytes, and pericytes. …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Greehey CCRI Receives Its First NIH K99 Award (Chen Lab)

March 2, 2020

      Yu-Chiao Chiu, PhD, a postdoctoral researcher at the Greehey Children’s Cancer Research Institute (GCCRI), received the prestigious NIH Pathway to Independence Award (K99/R00) from the National Cancer Institute (NCI). The highly co …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.

Clinical Cancer Research: EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma

March 1, 2020

Shaofang Wu 1, Feng Gao 1, Siyuan Zheng 2, Chen Zhang 1, Emmanuel Martinez-Ledesma 1 3, Ravesanker Ezhilarasan 4, Jie Ding 1, Xiaolong Li 1, Ningping Feng 5, Asha Multani 6, Erik P Sulman 4, Roel G Verhaak 2, John F de Groot 1, Tim P Heffernan 5, W K A …


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through the discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas: research, clinical, and education.

Stay connected with the Greehey CCRI on Facebook, Twitter, LinkedIn, and Instagram.