Future Focus: San Antonio lands one of its largest Cancer Grants to Bring in New Talent
February 27, 2020CPRIT officials said this is one of the largest amounts San Antonio institutions have collectively received from the institute in a single funding round since it was established by Texas voters in 2007. CPRIT CEO Wayne Roberts said it’s also further in …
Manjeet Rao, PhD, Awarded NCI, R01 Grant to Test Efficacy of Novel Drug
Dr. Manjeet Rao, Greehey CCRI Deputy Director (interim), was recently awarded a grant from National Cancer Institute ($2.1 million) to test the therapeutic efficacy of a novel drug that can inhibit the function of a protein that is highly expressed in …
Frontiers in Oncology: Nanoformulation of Talazoparib Increases Maximum Tolerated Doses in Combination With Temozolomide for Treatment of Ewing Sarcoma (Kurmasheva Lab)
Paige Baldwin1, Rostislav Likhotvorik2, Nabeela Baig2, Jodie Cropper2, Ruth Carlson2, Raushan Kurmasheva2,3*† and Srinivas Sridhar1,4,5*† The Pediatric Preclinical Testing Program previously identified the PARP inhibitor talazoparib (TLZ) as a me …
Greehey CCRI Faculty Awarded $1.2M CPRIT Grant to Support Osteosarcoma Research
Written by: Will Sansom An award of $1.2 million from the Cancer Prevention and Research Institute of Texas (CPRIT) went to Greehey CCRI Deputy Director and principal investigator Manjeet Rao, PhD, professor of cell systems and anatomy, for studies of …
Luiz O.F. Penalva, PhD, Co-corresponding Senior Author on NPJ Genomic Medicine publication.
“Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles” Abstract Therapy resistance and recurrence in high-grade gliomas are driven by their populations of glioma stem cells (GSCs). Thus, detailed molecul …
Pipette Gazette: Kevin Kanda, From Nursing Student To Graduate Student (Bishop Lab)
February 20, 2020Kevin Kanda made a promise to his family to try to fight cancer. “I’ve lost some family and friends to cancer….my uncle died from lymphoma and I’ve known people with pancreatic and breast cancer as well,” he said. Initially, Kanda thought nursing would …
San Antonio Business Journals: San Antonio lands one of its largest cancer grant allocations ever to bring in more talent
February 20, 2020CPRIT officials said this is one of the largest collective awards the Alamo City has received in a single funding round.
Advances in Urology: Microbiome within Primary Tumor Tissue from Renal Cell Carcinoma May Be Associated with PD-L1 Expression of the Venous Tumor Thrombus
February 18, 2020Michael A. Liss,1 Yidong Chen,2 Ronald Rodriguez,1 Deepak Pruthi,1 Teresa Johnson-Pais,3 Hanzhang Wang,1 Ahmed Mansour,1 James R. White,4 and Dharam Kaushik1 Abstract Objective. To perform a proof of concept microbiome evaluation and PD-L1 expression p …
Cell Stem Cell: Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis
February 6, 2020Zhe Zhu, Pinar Mesci, Jean A Bernatchez, Ryan C Gimple, Xiuxing Wang, Simon T Schafer, Hiromi I Wettersten, Sungjun Beck, Alex E Clark, Qiulian Wu, Briana C Prager, Leo JY Kim, Rekha Dhanwani, Sonia Sharma, Alexandra Garancher, Sara M Weis, Stephen C M …
Springer: Prospective use of the single-mouse experimental design for the evaluation of PLX038A
January 11, 2020Samson Ghilu, Qilin Li, Shaun D. Fontaine, Daniel V. Santi, Raushan T. Kurmasheva, Siyuan Zheng & Peter J. Houghton Abstract Purpose Defining robust criteria for drug activity in preclinical studies allows for fewer animals per treatment group, and …