Journal of Immunology: Immune Sensing of Aeroallergen-Associated Double-Stranded RNA Triggers an IFN Response and Modulates Type 2 Lung Inflammation
November 1, 2019Li She, Hamad H. Alanazi, Liping Yan, Yi Zou, Yilun Sun, Peter H. Dube, Edward G. Brooks, Gema D. Barrera, Zhao Lai, Yidong Chen, Yong Liu, Xin Zhang and Xiao-Dong Li Abstract The innate immune sensing of allergens or allergen-associated components reg …
MISSION MAGAZINE: Tiny molecule has big effect in childhood brain cancer (Rao Lab)
October 22, 2019Sometimes small things make the biggest difference. A new study has found that a molecule thousands of times smaller than a gene is able to kill medulloblastoma, the most common childhood brain cancer. This tiny molecule, named MiR-584-5p, is quite eff …
International Journal of Cancer: GD2‐directed CAR‐T cells in combination with HGF‐targeted neutralizing antibody (AMG102) prevent primary tumor growth and metastasis in Ewing sarcoma
October 17, 2019Manish Charan, Piyush Dravid, Maren Cam, Anthony Audino, Amy C. Gross, Michael A. Arnold, Ryan D. Roberts, Timothy P. Cripe, Alexander Pertsemlidis, Peter J. Houghton, Hakan Cam Abstract Ewing sarcoma (EWS) is the second most common and aggressive typ …
Human Mutation: Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276, and p.Lys1423: genotype-phenotype study in neurofibromatosis type 1
October 8, 2019Magdalena Koczkowska 1, Tom Callens 1, Yunjia Chen 1, Alicia Gomes 1, Alesha D Hicks 1, Angela Sharp 1, Eric Johns 1, Kim Armfield Uhas 2, Linlea Armstrong 3, Katherine Armstrong Bosanko 4, Dusica Babovic-Vuksanovic 5, Laura Baker 6, Donald G Basel 7, …
Review article “Challenges and Opportunities for Childhood Cancer Drug Development” co-authored by Drs Kurmasheva and Houghton
October 3, 2019The review article “Challenges and Opportunities for Childhood Cancer Drug Development” co-authored by Raushan Kurmasheva, PhD and Peter Houghton, PhD has just been published.
Pharmacology Reviews: Challenges and Opportunities for Childhood Cancer Drug Development
October 1, 2019Peter J Houghton 1, Raushan T Kurmasheva 2 Abstract Cancer in children is rare with approximately 15,700 new cases diagnosed in the United States annually. Through the use of multimodality therapy (surgery, radiation therapy, and aggressive chemotherap …
Cancer Research: Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma
October 1, 2019Xiaolong Li 1, Emmanuel Martinez-Ledesma 1 2, Chen Zhang 1, Feng Gao 1, Siyuan Zheng 1, Jie Ding 1, Shaofang Wu 1, Nghi Nguyen 3, Stephan C Clifford 3, Patrick Y Wen 4, Keith L Ligon 4, W K Alfred Yung 1, Dimpy Koul 5 Abstract PI3K-targeting therapy re …
WEBINAR: Childhood Cancer Survivorship, Transitioning to Adulthood (Aune Lab)
September 27, 2019REPOST from September 25th webinar originally broadcasted, September 25th, 2019 Childhood cancer advocates, families, researchers, and survivors are invited to join us for this Childhood Cancer Awareness Month event. We’ll have a robust discussion abou …
Molecular Therapy – Oncolytics: The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5
September 27, 2019Author links open overlay panelXiaojie Yu126, Yiqiang Zhang1, Binggen Wu13, Jonathan M.Kurie4, Alexander Pertsemlidis125 Chemoresistance and metastasis are the major reasons for non-small cell lung cancer (NSCLC) treatment failure and patient deaths. W …
KENS5: UT Health working to fight children’s cancer with Hyundai Hope on Wheels grant (Houghton, Aune, Ignatius mention)
September 24, 2019UT Health working to fight children’s cancer with Hyundai Hope on Wheels grant To help in the fight against pediatric cancer, Hyundai Hope on Wheels presented two grants totaling $500,000 to UT Health San Antonio. SAN ANTONIO — UT Health San Antonio is …