Panneerdoss Subbarayalu, PhD (Rao Lab) to Receive $879,000 American Cancer Society Grant
May 8, 2026Panneerdoss Subbarayalu, PhD American Cancer Society Research Scholar Grant Information Principal Investigator: Panneerdoss Subbarayalu, PhD, Co-Investigators: Dr. Peter Houghton, Dr. Gail Tomlinson, Dr. Yidong Chen, Dr. Suryavathi Viswanadhapalli, and …
What if we could stop chronic pain before it starts? (Lai Lab)
May 6, 2026Nature Communications: Highly mutagenic copying of telomeric circles promotes ALT establishment (Malkova Lab)
May 5, 2026Meng-Chia Tsai, Jacob M. Wells, Kelley A. Renninger, Kendra Musmaker, Ryan Pellow, Andrey Malkov, Josep M. Comeron & Anna Malkova Abstract Alternative lengthening of telomeres (ALT) is a recombination-based pathway that enables cancer cells to main …
Nature Structural & Molecular Biology: Structural insight into how RAD51 paralog exchange regulates RAD51 filament formation (Rao, Libich, Wasmuth, Sung, Olsen et al)
April 24, 2026Yashpal Rawal, Youngho Kwon, Lijia Jia, Eliza A. Ruben, Jae-Hoon Ji, Lijuan Guo, Caleb M. Stratton, Digant Nayak, Miriam Tovar, Qingming Fang, Mohd Azrin Jamalruddin, Shuo Zhou, Sahiti Kuppa, Shahrez Syed, Angela M. Jasper, Jeffrey N. Katz, Cody M. Rog …
Science Advances: Selective elimination of circulating effector CD8 T cells via LTβR blockade separates anti-CD137 efficacy from toxicity (Lai, Chen)
April 24, 2026Sergey A. Shein Anna A. Korchagina Li-Ju Wang Zhao Lai, Yidong Chen Jacob S. Fisher Burkhard Ludewig Jessica N. Lancaster Yang-Xin Fu , Ekaterina Koroleva and Alexei V. Tumanov Abstract The major barrier to clinical translation of αCD137 immunothe …
Journal of Applied Physiology: Hyperactive Muscle mTORC1 Attenuates Functional Adaptations to Endurance Training Despite Alterations in Mitochondrial and Lipid Profiles (Lai Lab)
April 24, 2026Abstract Mechanistic target of rapamycin complex I (mTORC1) is a key regulator of cell growth and metabolism, and its activity increases with aging. Hyperactivation of mTORC1 is associated with the pathology of sarcopenia and mitochondrial dysfunction. …
Ubiquitylation of DNA polymerase β via atypical K27 chains signals a DNA damage response (Sung Lab)
April 16, 2026Qingming Fang , Christopher A Koczor , Wynand P Roos , Steve McClellan , Joel F Andrews , Robert W Sobol Abstract DNA polymerase β (Polβ) stability is tightly regulated by specific binding partners that prevent its proteasomal degradation. Ubiquit …
David Libich, PhD Awarded Five‑Year, $2.1 million NIH Grant to Study “Protein Intrinsic Disorder in Genome Regulation.”
April 13, 2026Every cell in the body must carefully protect its DNA to stay healthy. To do this, cells coordinate several essential tasks, such as turning genes on and off, processing genetic information, and repairing damaged DNA. These activities occur within the …
Journal of Biological Chemistry: Structural Basis for the Mechanism and Stability of the EEPD1 5’ Endonuclease (Gupta Lab)
April 10, 2026Robert A. Hromas1,∗ guptay@uthscsa.edu ∙ Aruna S. Jaiswal1,∗ ∙ Anurag Misra2,∗ ∙ Yaxia Yuan3 ∙ Daohong Zhou3 ∙ John I. Beckman2 ∙ Shailee Arya2 ∙ Adhishree Chidambaram2 ∙ Alexander B. Taylor2 ∙ Wendell Griffith4 ∙ Arunima Jaiswal1 ∙ Elizabeth A. Willia …
Graduate School of Biomedical Sciences (GSBS) Outstanding Student Awards
April 8, 2026We at Greehey CCRI are proud to celebrate the exceptional achievements of our GSBS students, whose leadership and research are making a meaningful impact across our academic community. 🌟 GSBS Outstanding Student Leadership Award: Jack Prochnau The Outs …