Protein Science: Molecular basis of EWS interdomain self-association and its role in condensate formation (Libich Lab)
September 22, 2025Erich J. Sohn, Kandarp A. Sojitra, Leticia Rodrigues, Xiaoping Xu, Bess Frost, Jeetain Mittal, David S. Libich Abstract Ewing sarcoma, the second most common pediatric bone and soft tissue cancer, is caused by the aberrant fusion of the RNA-binding pro …
Trends in Biochemical Sciences: E3 Ubiquitin Ligases in Signaling, Disease, and Therapeutics (Olsen)
September 15, 2025Pirouz Ebadi 1, Caleb M Stratton 1, Shaun K Olsen 2 Abstract The ubiquitin-proteasome system (UPS) is a central regulator of protein turnover and signaling, with E3 ubiquitin ligases conferring substrate specificity and chain-type control. Recent advan …
Aging Cell: Inhibition of Hippo Signaling Through Ablation of Lats1 and Lats2 Protects Against Cognitive Decline in 5xFAD Mice via Increasing Neuronal Resilience Against Ferroptosis (Zheng)
September 10, 2025Robert C. Evans, Nawab John Dar, Liuji Chen, Ren Na, Jason C. O’Connor, Jing Jiang, Siyuan Zheng, Qitao Ran ABSTRACT The Hippo signaling pathway is a key regulator of cell growth and cell survival, and hyperactivation of the Hippo pathway has been impl …
Expert Opinion on Therapeutic Targets: Rhabdomyosarcoma: development of molecular therapeutics under the microscope (Houghton)
August 15, 2025Peter J. Houghton Mary-Ann Bjornsti ABSTRACT Rhabdomyosarcoma (RMS), predominantly diagnosed in children, represents 3% of the pediatric solid tumors. RMS has characteristics of skeletal muscle, although the cell of origin remains controversial. Cytoto …
🎉Congratulations to Chris Do (Rao Lab) for being named the UT Health San Antonio Graduate School of Biomedical Sciences Sr. Student of the Year!
The GSBS Senior Student of the Year Award recognizes a graduate student who demonstrates the best potential for research success as measured by publications, presentations, and awards. The student must demonstrate sustained excellence in academics. Chr …
Dr. Yogesh Gupta, PhD Selected to Receive the Graduate Mentor of the Year Award at the 2025 GSBS Convocation Ceremony
Dr. Yogesh Gupta, Ph.D. Graduate Mentor of the Year Award Recipient Dr. Robert Svatek, M.D., M.S.C.I. Graduate Mentor of the Year Award Recipient We are thrilled to announce that Dr. Yogesh Gupta, Ph.D., and Dr. Robert Svatek, M.D., M.S.C.I., are the r …
KENS5 & Great Day SA, Hyundai Hope on Wheels Handprint Ceremony (Tomlinson)
August 11, 2025Gail Tomlinson, MD, PhD, professor of pediatrics and division chief of pediatric hematology-oncology in the Department of Pediatrics at UT Health San Antonio, was interviewed by KENS-TV and appeared on the station’s morning show, “Great Day SA.” Dr. To …
Biochemistry: The Spliceosomal Peptidyl Prolyl Isomerase Like 1 Interacts with the Low-Complexity Domain of the RNA Binding Protein EWS Modulating Its Phase Separation Behavior (Libich Lab)
August 8, 2025George L Parra 1, Erich J Sohn 1, Xiaoping Xu 1, David S Libich 1 Abstract RNA-binding protein EWS, a member of the FET (FUS, EWS, TAF15) family, contributes to mRNA biogenesis through roles in transcription, splicing, and RNA transport. Despite eviden …
UT Health San Antonio gears up to drive out childhood cancer (Hyundai Hope on Wheels Media Advisory)
August 5, 2025FOR IMMEDIATE RELEASE August 5, 2025 Contact: Eileen Teves, 210-450-7239, tevese@uthscsa.edu MEDIA ADVISORY UT Health San Antonio gears up to drive out childhood cancer Receives grant from Hyundai Hope on Wheels® to continue its fight against the disea …