Greehey CCRI Archives
Emily Selig of Libich Lab, Awarded a Spot on CPRIT Training Grant
January 8, 2021Emily Selig recently earned her PhD at the University of Melbourne, Australia where she was employing biophysical and biochemical approaches to investigate the mechanisms by which the small heat-shock proteins aB-crystallin and hea …
MDPI: MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation
December 5, 2020Rebecca Pötschke 1,2,† Jacob Haase 1,†, Markus Glaß 1 Sebastian Simmermacher 3,Claudia Misiak 1,Luiz O. F. Penalva 4,5 Caspar D. Kühnöl, 2 and Stefan Hüttelmaier 1, Simple Summary Glioblastoma (GBM) is the most lethal brain tumor with a median su …
Molecular Oncology: Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling
December 2, 2020Junhao Liu, Zexuan Liu, Mengxing Li, , Weiwei Tang, Uday P. Pratap, Yiliao Luo, Kristin A. Altwegg, Xiaonan Li, Yi Zou, Hong Zhu, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Ratna K. Vadlamudi Abstract A significant proportion of estrogen recep …
PNAS: Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibility
November 24, 2020Yuan Lu, View ORCID ProfileAngel Sandoval, View ORCID ProfileSarah Voss, Zhao Lai, Susanne Kneitz, Will Boswell, Mikki Boswell, Markita Savage, View ORCID ProfileChristi Walter, Wes Warren, View ORCID ProfileManfred Schartl, and Ronald Walter Abstr …
Mucosal Immunology: Campylobacter infection promotes IFNγ-dependent intestinal pathology via ILC3 to ILC1 conversion
November 19, 2020Wayne T. Muraoka, Anna A. Korchagina, Qingqing Xia, Sergey A. Shein, Xi Jing, Zhao Lai, Korri S. Weldon, Li-Ju Wang, Yidong Chen, Lawrence W. Kummer, Markus Mohrs, Eric Vivier, Ekaterina P. Koroleva & Alexei V. Tumanov Abstract Innate lymphoid cell …
Nature Communications: Integrative transcriptome and chromatin landscape analysis reveals distinct epigenetic regulations in human memory B cells (Pertsemlidis)
November 16, 2020Justin B. Moroney, Anusha Vasudev, Alexander Pertsemlidis, Hong Zan & Paolo Casali Abstract Memory B cells (MBCs) are long-lived and produce high-affinity, generally, class-switched antibodies. Here, we use a multiparameter approach involving CD27 …
Argonne National Laboratory: Hide and Seek: Understanding How COVID-19 Evades Detection in a Human Cell (Gupta)
November 3, 2020BY ANDRE SALLES |OCTOBER 29, 2020 Scientists using the Advanced Photon Source have discovered new insights into the ways the SARS-CoV-2 virus camouflages itself inside the human body. Scientists around the world have been working for months to identify …
Cell Reports: GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
November 3, 2020Fuchun Zhou (1), David J.Elzi (1, 2), Panneerselvam Jayabal(1), Xiuye Ma(1), Yu-Chiao Chiu (1) Yidong Chen 1,3,4) Barron Blackman(1) Susan T.Weintraub (4, 5) Peter J.Houghton 1,4,6) Yuzuru Shiio (1,4,5,7) Highlights The autocrine signaling mediated by …
ECancer Interview: Prospective validation of single mouse testing by the paediatric preclinical testing consortium (Houghton)
October 24, 2020Dr. Peter Houghton speaks to ecancer about the prospective validation of single mouse testing by the pediatric preclinical testing consortium; a study that was presented at ENA 2020 this year. Dr. Houghton initially explains the rationale behind this s …
MedicalXpress – One Mouse at a Time: a New Approach to Testing Potential Drugs for Children’s Cancers (Houghton, Kurmasheva, PPTC)
October 22, 2020by European Organisation for Research and Treatment of Cancer A team of researchers in the US and Australia have developed a way of testing potential drugs for children’s cancers so as to take account of the wide genetic diversity of these diseases. In …