Greehey CCRI News & Events Archive

Filter results


 

Pathobiology of Aging & Age-related Diseases: Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy

August 24, 2015

Xiang Bai, Margaret Chia-Ying Wey, Elizabeth Fernandez, Matthew J. Hart, Jonathan Gelfond, Alex F. Bokov, Sheela Rani & Randy Strong Abstract Background Synucleinopathy is any of a group of age-related neurodegenerative disorders including Parkinso …


Molecular Cancer Research: ZBTB7A Suppresses Melanoma Metastasis by Transcriptionally Repressing MCAM

August 1, 2015

Xue-Song Liu, Matthew D. Genet, Jenna E. Haines, Elie K. Mehanna, Shaowei Wu, Hung-I Harry Chen, Yidong Chen, Abrar A. Qureshi, Jiali Han, Xiang Chen, David E. Fisher, Pier Paolo Pandolfi, and Zhi-Min Yuan Abstract The excessive metastatic propensity o …


National Coalition for Cancer Survivorship: Guest Post: Oncologist and Cancer Survivor Greg Aune Talks Multi-Disciplinary Care

July 31, 2015

The Importance of Multidisciplinary Survivorship Care and Research Post by Greg Aune, MD, PhD, Greehey Children’s Cancer Research Institute, Univ. of Texas Health Science Center at San Antonio Survivors of cancer are a growing population in the United …


Biology of Reproduction: Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice

July 1, 2015

Joshua P. Welborn, Matthew G. Davis, Steven D. Ebers, Genna R. Stodden, Kanako Hayashi, Joseph L. Cheatwood, Manjeet K. Rao, James A. MacLean, II Abstract The reproductive homeobox X-linked, Rhox, genes encode transcription factors that are selectively …


BMC Genomics: Co-modulation analysis of gene regulation in breast cancer reveals complex interplay between ESR1 and ERBB2 genes

June 11, 2015

Yu-Chiao Chiu, Chin-Ting Wu, Tzu-Hung Hsiao, Yi-Pin Lai, Chuhsing Kate Hsiao, Yidong Chen & Eric Y Chuang Abstract Background Gene regulation is dynamic across cellular conditions and disease subtypes. From the aspect of regulation under modulation …


BMC Genomics: Education, collaboration, and innovation: intelligent biology and medicine in the era of big data

June 11, 2015

Jianhua Ruan, Victor Jin, Yufei Huang, Hua Xu, Jeremy S Edwards, Yidong Chen & Zhongming Zhao Abstract Here we present a summary of the 2014 International Conference on Intelligent Biology and Medicine (ICIBM 2014) and the editorial report of the s …


BMC Genomics: Differential expression analysis of RNA sequencing data by incorporating non-exonic mapped reads

June 11, 2015

Hung-I Harry Chen, Yuanhang Liu, Yi Zou, Zhao Lai, Devanand Sarkar, Yufei Huang & Yidong Chen Abstract Background RNA sequencing (RNA-seq) is a powerful tool for genome-wide expression profiling of biological samples with the advantage of high-thro …


Endocrine-Related Cancer: Integrity of the pheochromocytoma susceptibility TMEM127 gene in patients with pediatric malignancies

June 1, 2015

Authors: E E King 1 , Y Qin 1 , R A Toledo 1 , A Luo 1 , E Ball 1 , F R Faucz 1 , K A Janeway1 , C A Stratakis 1 , G E Tomlinson 1 , 1 , 1 , and P L M Dahia 1 , 1 , 1 Dear Editor, Germline mutations of the tumor suppressor gene TMEM127 occur in the neu …


RNA Biology: microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest

May 6, 2015

Zhenze ZhaoGreehey Children’s Cancer Research Institute; ,Xiuye Ma,Derek Sung,Monica Li,Adam Kosti,Gregory Lin,Yidong Chen,Alexander Pertsemlidis,Tzu-Hung Hsiao &Liqin Du Abstract microRNA-449a (miR-449a) has been identified to function as a tumor …


BMC Genomics: HEPeak: an HMM-based exome peak-finding package for RNA epigenome sequencing data

April 21, 2015

Xiaodong Cui, Jia Meng, Manjeet K Rao, Yidong Chen & Yufei Huang Abstract Background Methylated RNA Immunoprecipitation combined with RNA sequencing (MeRIP-seq) is revolutionizing the de novo study of RNA epigenomics at a higher resolution. However …


Secured By miniOrange