Greehey CCRI Archives
KSAT12: $10+ million grant helps survivor now working at cancer institute that saved him (Houghton, Chen, Ignatius, Shiio, mention)
June 17, 2016SAN ANTONIO – The doctors, staff and patients at the Greehey Children’s Cancer Research Institute are celebrating its latest grant, a $10.9 million donation from Cancer Prevention and Research Institute of Texas.
SA Business Journal: Cancer money to boost local pediatric research
June 3, 2016The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Pat …
UT Health SA Newsroom: CPRIT awards $10.9 million to Greehey institute for cancer research
May 20, 2016The Greehey Children’s Cancer Research Institute at the Health Science Center garnered $10.9 million from the Cancer Prevention & Research Institute of Texas (CPRIT)―a larger amount than any other academic institution in the state. The Health Scien …
UT Health SA Newsroom: CPRIT awards $10.9 million to Greehey institute for cancer research
May 20, 2016The Greehey Children’s Cancer Research Institute at the Health Science Center garnered $10.9 million from the Cancer Prevention & Research Institute of Texas (CPRIT)―a larger amount than any other academic institution in the state. The Health Scien …
Cancer Chemotherapy and Pharmacology: Identifying novel therapeutic agents using xenograft models of pediatric cancer
May 18, 2016Raushan T. Kurmasheva & Peter J. Houghton Abstract In the USA, the overall cure rate for all childhood cancers is seventy percent, and in many patients that ultimately fail curative therapy, initial responses to current multimodality treatments (su …
Molecular Cancer Therapy: The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma
May 15, 2016Hemant K Bid 1, Doris A Phelps 1, Linlin Xaio 1, Denis C Guttridge 2, Jiayuh Lin 1, Cheryl London 3, Laurence H Baker 4, Xiaokui Mo 5, Peter J Houghton 6 Abstract The bromodomain and extra-terminal domain inhibitor JQ1 has marked antitumor activity aga …
Biochimica et Biophysica Acta (BBA) – Molecular Basis of Disease: Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer’s disease
May 1, 2016Abstract Aging is the strongest known risk factor for Alzheimer’s disease (AD). With the discovery of the mechanistic target of rapamycin (mTOR) as a critical pathway controlling the rate of aging in mice, molecules at the interface between the regulat …
Clinical Cancer Research: Recurrent Mutations of Chromatin-Remodeling Genes and Kinase Receptors in Pheochromocytomas and Paragangliomas
May 1, 2016Rodrigo A. Toledo, Yuejuan Qin, Zi-Ming Cheng, Qing Gao, Shintaro Iwata, Gustavo M. Silva, Manju L. Prasad, I. Tolgay Ocal, Sarika Rao, Neil Aronin, Marta Barontini, Jan Bruder, Robert L. Reddick, Yidong Chen, Ricardo C.T. Aguiar and Patricia L.M. Dahi …
PLOS One: Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human
April 21, 2016Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis H. T. de Souza, José C. F. Moreira, Uthra Suresh, Yidong Chen, Alexander J. R. Bishop Abstract Alkylating agents are a key component of cancer chemotherapy. Several cellular mechanisms are known …
PLOS One: Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human
April 21, 2016Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis H. T. de Souza, José C. F. Moreira, Uthra Suresh, Yidong Chen, Alexander J. R. Bishop Abstract Alkylating agents are a key component of cancer chemotherapy. Several cellular mechanisms are know …