Greehey CCRI Archives
PLOS One: Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human
April 21, 2016Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis H. T. de Souza, José C. F. Moreira, Uthra Suresh, Yidong Chen, Alexander J. R. Bishop Abstract Alkylating agents are a key component of cancer chemotherapy. Several cellular mechanisms are known …
PLOS One: Combined Gene Expression and RNAi Screening to Identify Alkylation Damage Survival Pathways from Fly to Human
April 21, 2016Alfeu Zanotto-Filho, Ravi Dashnamoorthy, Eva Loranc, Luis H. T. de Souza, José C. F. Moreira, Uthra Suresh, Yidong Chen, Alexander J. R. Bishop Abstract Alkylating agents are a key component of cancer chemotherapy. Several cellular mechanisms are know …
JCI Insight: Synergism of FAK and tyrosine kinase inhibition in Ph+ B-ALL
April 17, 2016Michelle L. Churchman,1 Kathryn Evans,2 Jennifer Richmond,2 Alissa Robbins,2 Luke Jones,2 Irina M. Shapiro,3 Jonathan A. Pachter,3 David T. Weaver,3 Peter J. Houghton,4 Malcolm A. Smith,5 Richard B. Lock,2 and Charles G. Mullighan1 Abstract BCR-ABL1+ B …
Genes & Cancer: FGF19 functions as autocrine growth factor for hepatoblastoma
April 6, 2016David J. Elzi1, Meihua Song1, Barron Blackman1, Susan T. Weintraub2, Dolores López-Terrada5, Yidong Chen1,3, Gail E. Tomlinson1,4 and Yuzuru Shiio1,2 ABSTRACT Hepatoblastoma is the most common liver cancer in children, accounting for over 65% of all ch …
RNA Biology: High-throughput analyses of hnRNP H1 dissects its multi-functional aspect
April 2, 2016Authors Philip J Uren, Emad Bahrami-Samani, Patricia Rosa de Araujo, Christine Vogel, Mei Qiao, Suzanne C Burns, Andrew D Smith, Luiz OF Penalva hnRNPs are polyvalent RNA binding proteins that have been implicated in a range of regulatory roles includi …
Journal of Community Support Oncology: Reaching high-risk underserved individuals for cancer genetic counseling by video-teleconferencing
April 1, 2016Lindsey A Mette 1 2, Anna Maria Pulido Saldívar 2 3, Natalie E Poullard 1 2, Ivette C Torres 2 4, Sarah G Seth 1 2, Brad H Pollock 5 6, Gail E Tomlinson 7 2 6 Abstract Background: Breast and colorectal cancers are common cancers for which genetic risk …
Experimental Biology and Medicine: Original Research: A case-control genome-wide association study identifies genetic modifiers of fetal hemoglobin in sickle cell disease
March 27, 2016Li Liu, Alexander Pertsemlidis, Liang-Hao Ding, Michael D Story, Martin H Steinberg, Paola Sebastiani, Carolyn Hoppe, Samir K Ballas, Betty S Pace Abstract Sickle cell disease (SCD) is a group of inherited blood disorders that have in common a mutation …
Pediatric Blood & Cancer: Initial Testing of NSC 750854, a Novel Purine Analog, Against Pediatric Tumor Models by the Pediatric Preclinical Testing Program
March 1, 2016Richard Gorlick 1, E Anders Kolb 2, Stephen T Keir 3, John M Maris 4, Richard B Lock 5, Hernan Carol 5, C Patrick Reynolds 6, Min H Kang 6, Catherine A Billups 7, Jerry Collins 8, Dias Kurmashev 9, Raushan T Kurmasheva 9, Peter J Houghton 9, Malcolm A …
Scientific Report: Roles of Distal and Genic Methylation in the Development of Prostate Tumorigenesis Revealed by Genome-wide DNA Methylation Analysis
February 29, 2016Yao Wang 1, Rohit Ramakant Jadhav 1, Joseph Liu 1, Desiree Wilson 2, Yidong Chen 3, Ian M Thompson 4 5, Dean A Troyer 6, Javier Hernandez 4, Huidong Shi 7, Robin J Leach 2 4 5, Tim H-M Huang 1 5, Victor X Jin 1 3 Abstract Aberrant DNA methylation at pr …
Pediatric Blood & Cancer: Pharmacodynamic and genomic markers associated with response to the XPO1/CRM1 inhibitor selinexor (KPT-330): A report from the pediatric preclinical testing program
February 1, 2016Edward F Attiyeh, John M Maris 1, Richard Lock 2, C Patrick Reynolds 3, Min H Kang 3, Hernan Carol 2, Richard Gorlick 4, E Anders Kolb 5, Stephen T Keir 6, Jianrong Wu 7, Yosef Landesman 8, Sharon Shacham 8, Dmitry Lyalin 9, Raushan T Kurmasheva 9, Pet …