Greehey CCRI News & Events Archive
Luiz O.F. Penalva, Ph.D., Co-corresponding Senior Author on NPJ Genomic Medicine publication.
“Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles” Abstract Therapy resistance and recurrence in high-grade gliomas are driven by their populations of glioma stem cells (GSCs). Thus, detailed molecul …
Advances in Urology: Microbiome within Primary Tumor Tissue from Renal Cell Carcinoma May Be Associated with PD-L1 Expression of the Venous Tumor Thrombus
February 18, 2020Michael A. Liss,1 Yidong Chen,2 Ronald Rodriguez,1 Deepak Pruthi,1 Teresa Johnson-Pais,3 Hanzhang Wang,1 Ahmed Mansour,1 James R. White,4 and Dharam Kaushik1 Abstract Objective. To perform a proof of concept microbiome evaluation and PD-L1 expression p …
Cell Stem Cell: Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis
February 6, 2020Zhe Zhu, Pinar Mesci, Jean A Bernatchez, Ryan C Gimple, Xiuxing Wang, Simon T Schafer, Hiromi I Wettersten, Sungjun Beck, Alex E Clark, Qiulian Wu, Briana C Prager, Leo JY Kim, Rekha Dhanwani, Sonia Sharma, Alexandra Garancher, Sara M Weis, Stephen C M …
NPJ Genomic Medicine: Proneural and mesenchymal glioma stem cells display major differences in splicing and lncRNA profiles
January 16, 2020Gabriela DA Guardia, Bruna R Correa, Patricia Rosa Araujo, Mei Qiao, Suzanne Burns, Luiz OF Penalva, Pedro AF Galante Abstract Therapy resistance and recurrence in high-grade gliomas are driven by their populations of glioma stem cells (GSCs). Thus, de …
Springer: Prospective use of the single-mouse experimental design for the evaluation of PLX038A
January 11, 2020Samson Ghilu, Qilin Li, Shaun D. Fontaine, Daniel V. Santi, Raushan T. Kurmasheva, Siyuan Zheng & Peter J. Houghton Abstract Purpose Defining robust criteria for drug activity in preclinical studies allows for fewer animals per treatment group, and …
Adam Kosti Publishes First, First-Author Paper (Penalva Lab)
January 10, 2020ELF4 is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State Abstract 13-Cis-retinoic acid (RA) is typically used in postremission maintenance therapy in patients with neuroblastoma. However, side effects and recurren …
Endocrinology: Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer
January 2, 2020Sulgi Park, Chung-Seog Song, Chun-Lin Lin, Shoulei Jiang, Pawel A Osmulski, Chiou-Miin Wang, Brett T Marck, Alvin M Matsumoto, Colm Morrissey, Maria E Gaczynska, Yidong Chen, Elahe A Mostaghel, Bandana Chatterjee Abstract SULT2B1b (SULT2B) is a prostat …
Frontiers in Biosciences (Elite Ed) Cytogenetics of hepatoblastoma
January 2, 2020Gail E Tomlinson 1 Abstract The cytogenetics of hepatoblastoma demonstrate recurring events which include whole chromosome trisomies, most commonly trisomy of chromosome 2, 8, or 10. In addition, unbalanced translocations involving a breakpoint on the …
Molecular Cancer Research: ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state
January 1, 2020Adam Kosti, Liqin Du, Haridha Shivram, Mei Qiao, Suzanne Burns, Juan Gabriel Garcia, Alexander Pertsemlidis, Vishwanath R Iyer, Erzsebet Kokovay, Luiz OF Penalva 13-Cis-retinoic acid (RA) is typically used in postremission maintenance therapy in patien …