Greehey CCRI Archives
PNAS: Oncogenic allelic interaction in Xiphophorus highlights hybrid incompatibility
November 24, 2020Yuan Lu, View ORCID ProfileAngel Sandoval, View ORCID ProfileSarah Voss, Zhao Lai, Susanne Kneitz, Will Boswell, Mikki Boswell, Markita Savage, View ORCID ProfileChristi Walter, Wes Warren, View ORCID ProfileManfred Schartl, and Ronald Walter Abstr …
Mucosal Immunology: Campylobacter infection promotes IFNγ-dependent intestinal pathology via ILC3 to ILC1 conversion
November 19, 2020Wayne T. Muraoka, Anna A. Korchagina, Qingqing Xia, Sergey A. Shein, Xi Jing, Zhao Lai, Korri S. Weldon, Li-Ju Wang, Yidong Chen, Lawrence W. Kummer, Markus Mohrs, Eric Vivier, Ekaterina P. Koroleva & Alexei V. Tumanov Abstract Innate lymphoid cell …
Breast Cancer Research and Treatment: KDM1A inhibition is effective in reducing stemness and treating triple negative breast cancer
October 14, 2020Abstract Purpose Cancer stem cells (CSCs) are highly tumorigenic, spared by chemotherapy, sustain tumor growth, and are implicated in tumor recurrence after conventional therapies in triple-negative breast cancer (TNBC). Lysine-specific histone demethy …
Scientific Reports: “Transcriptomic Sex Differences in Sensory Neuronal Populations of Mice”
September 23, 2020Jennifer Mecklenburg 1, Yi Zou 2, Andi Wangzhou 3, Dawn Garcia 2, Zhao Lai 2 4, Alexei V Tumanov 5, Gregory Dussor 3, Theodore J Price 3, Armen N Akopian 6 7 Abstract Many chronic pain conditions show sex differences in their epidemiology. This could b …
Scientific Reports: Transcriptomic sex differences in sensory neuronal populations of mice
September 17, 2020Jennifer Mecklenburg 1, Yi Zou 2, Andi Wangzhou 3, Dawn Garcia 2, Zhao Lai 2 4, Alexei V Tumanov 5, Gregory Dussor 3, Theodore J Price 3, Armen N Akopian 6 7 Abstract Many chronic pain conditions show sex differences in their epidemiology. This could b …
PNAS: Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection
August 3, 2020Rebecca K Lane 1, Hongyan Guo 2, Amanda D Fisher 1, Jonathan Diep 3, Zhao Lai 4 5, Yidong Chen 5 6, Jason W Upton 7, Jan Carette 3, Edward S Mocarski 8, William J Kaiser 9 Abstract Herpesviruses are ubiquitous human pathogens that cause a wide range of …
BMC: Age-associated genes in human mammary gland drive human breast cancer progression
June 15, 2020Xiang Gu, Bingzhi Wang, Haiyan Zhu, You Zhou, Aaron M. Horning, Tim H-M Huang, Yidong Chen, Peter Houghton, Zhao Lai, Joel E. Michalek & Lu-Zhe Sun Abstract Background Aging is a comorbidity of breast cancer suggesting that aging-associated transcr …
Clinical Cancer Research: Evaluation of Eribulin Combined with Irinotecan for Treatment of Pediatric Cancer Xenografts
June 1, 2020Andrew J. Robles, Raushan T. Kurmasheva, Abhik Bandyopadhyay, Doris A. Phelps, Stephen W. Erickson, Zhao Lai, Dias Kurmashev, Yidong Chen, Malcom A. Smith, and Peter J. Houghton Abstract Purpose: Vincristine combined with camptothecin derivatives showe …
Nature Cell Biology: Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance
May 18, 2020Mingjun Bi 1, Zhao Zhang 1, Yi-Zhou Jiang 2, Pengya Xue 1, Hu Wang 1, Zhao Lai 1, Xiaoyong Fu 3, Carmine De Angelis 3, Yue Gong 2, Zhen Gao 4, Jianhua Ruan 1 4, Victor X Jin 1, Elisabetta Marangoni 5, Elodie Montaudon 5, Christopher K Glass 6, Wei Li 7 …
Trauma & Acute Care Surgery: The gut microbiome distinguishes mortality in trauma patients upon admission to the emergency department
May 1, 2020Burmeister, David M. PhD; Johnson, Taylor R. BS; Lai, Zhao PhD; Scroggins, Shannon R. MS; DeRosa, Mark CRT; Jonas, Rachelle B. RN; Zhu, Caroline BS; Scherer, Elizabeth MD, MPH; Stewart, Ronald M. MD, FACS; Schwacha, Martin G. PhD; Jenkins, Donald H. MD …