Greehey CCRI Archives
International Journal of Genomics: Noncoding RNAs and Base Modifications: Epigenomic Players Implicated in Neurological Disorders and Tumorigenesis
June 13, 2018Zhen Wei,1,2 Subbarayalu Panneerdoss,3,4 Santosh Timilsina,3,4 Jingting Zhu,1,5 Tabrez A. Mohammad,3 Zhi-Liang Lu,1,5 João Pedro de Magalhães,2 Yidong Chen,3,6 Rong Rong,1,5 Yufei Huang,6,7 Manjeet K. Rao,3,4 and Jia Meng1,5 Abstract Background. Compar …
UT Health SA Newsroom: Greehey Institute begins 2018 with new faculty studying children’s cancer
January 18, 2018The Greehey Children’s Cancer Research Institute at UT Health San Antonio is on an impressive and rising trajectory as 2018 begins. This includes the recruitment of seven new faculty members, further bolstering the Alamo City’s thriving biosciences sec …
Nature Communications: Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells
September 19, 2017Subbarayalu Panneerdoss, Suryavathi Viswanadhapalli, Nourhan Abdelfattah, Benjamin C. Onyeagucha, Santosh Timilsina, Tabrez A. Mohammad, Yidong Chen, Michael Drake, Kristiina Vuori, T. Rajendra Kumar & Manjeet K. Rao Abstract Phagocytic clearance o …
Oncotarget: Novel post-transcriptional and post-translational regulation of pro-apoptotic protein BOK and anti-apoptotic protein Mcl-1 determine the fate of breast cancer cells to survive or die
September 12, 2017Benjamin Onyeagucha1,2, Panneerdoss Subbarayalu1,2, Nourhan Abdelfattah1,2, Subapriya Rajamanickam1,2, Santosh Timilsina1,2, Rosa Guzman1, Carla Zeballos2, Vijay Eedunuri1,2, Sanjay Bansal1, Tabrez Mohammad2, Yidong Chen1,3, Ratna K. Vadlamudi4, and Ma …
BMC Genomics: A hierarchical model for clustering m6A methylation peaks in MeRIP-seq data
August 22, 2016Xiaodong Cui, Jia Meng, Shaowu Zhang, Manjeet K. Rao, Yidong Chen & Yufei Huang Abstract Background The recent advent of the state-of-art high throughput sequencing technology, known as Methylated RNA Immunoprecipitation combined with RNA sequencin …
Clinical Cancer Research: Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis
July 1, 2016Subapriya Rajamanickam, Subbarayalu Panneerdoss, Aparna Gorthi, Santosh Timilsina, Benjamin Onyeagucha, Dmytro Kovalsky, Dmitri Ivanov, Martha A. Hanes, Ratna K. Vadlamudi, Yidong Chen, Alexander J. Bishop, Jack L. Arbiser and Manjeet K. Rao Abstract P …
Biology of Reproduction: Rhox8 Ablation in the Sertoli Cells Using a Tissue-Specific RNAi Approach Results in Impaired Male Fertility in Mice
July 1, 2015Joshua P. Welborn, Matthew G. Davis, Steven D. Ebers, Genna R. Stodden, Kanako Hayashi, Joseph L. Cheatwood, Manjeet K. Rao, James A. MacLean, II Abstract The reproductive homeobox X-linked, Rhox, genes encode transcription factors that are selectively …
BMC Genomics: HEPeak: an HMM-based exome peak-finding package for RNA epigenome sequencing data
April 21, 2015Xiaodong Cui, Jia Meng, Manjeet K Rao, Yidong Chen & Yufei Huang Abstract Background Methylated RNA Immunoprecipitation combined with RNA sequencing (MeRIP-seq) is revolutionizing the de novo study of RNA epigenomics at a higher resolution. However …
Journal of Biological Chemistry: Hormone-induced and DNA Demethylation-induced Relief of a Tissue-specific and Developmentally Regulated Block in Transcriptional Elongation*
December 19, 2014Abstract Genome-wide studies have revealed that genes commonly have a high density of RNA polymerase II just downstream of the transcription start site. This has raised the possibility that genes are commonly regulated by transcriptional elongation, bu …
Nucleic Acids Research: MeT-DB: a database of transcriptome methylation in mammalian cells
November 6, 2014Hui Liu, Mario A Flores, Jia Meng, Lin Zhang, Xinyu Zhao, Manjeet K. Rao, Yidong Chen, Yufei Huang Abstract Methyltranscriptome is an exciting new area that studies the mechanisms and functions of methylation in transcripts. The MethylTranscriptome Dat …