Greehey CCRI Archives

Filter results


 

Nicole Hensch (Ignatius Lab) Successfully Defends PhD Thesis!

May 17, 2022

“SNAI2 protection of rhabdomyosarcoma against ionizing radiation can be targeted through MEK inhibition in RAS-mutant fusion-negative tumors”               Nicole Hensch Mentor: Myron Ignatius, PhD Program: PhD Integr …


Successful PhD Thesis Defense: Santosh Timilsina (Rao Lab)

May 13, 2022

“Targeting Forkhead Box M1 as a Novel Approach to Inhibit Breast Cancer Growth and Progression” Santosh Timilsina Mentor:  Manjeet Rao, PhD Program: PhD Integrated Biomedical Sciences Cell Biology – Cancer Biology Discipline


JCO Oncology Practice: Disparities in Cancer Genetic Testing and Variants of Uncertain Significance in the Hispanic Population of South Texas (Tomlinson Lab, Ignatius Lab)

May 12, 2022

Stephanie Soewito, BS, MS1; Rachel Wyatt, MS2; Emily Berenson, MS2; Natalie Poullard, MS, MA3; Shawn Gessay, MS2,3,4; Lindsey Mette, MS, MPH2,3,5; Elena Marin, CHW6; Kristin Shelby, BA6; Elise Alvarez, BA3; Byeong Yeob Choi, PhD7; Clarissa Aviles, MSHS …


Nature Communications: Bloom helicase mediates formation of large single–stranded DNA loops during DNA end processing (Sung)

April 27, 2022

Chaoyou Xue, Sameer J. Salunkhe, Nozomi Tomimatsu, Ajinkya S. Kawale, Youngho Kwon, Sandeep Burma, Patrick Sung & Eric C. Greene Nature Communications volume 13, Article number: 2248 (2022) Cite this article Abstract Bloom syndrome (BS) is associat …


Molecular Carcinogenesis: SIRT1 inhibition-induced senescence as a strategy to prevent prostate cancer progression (Chen, Lai)

April 25, 2022

Abstract Emerging evidence suggests an important role for SIRT1, a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase in cancer development, progression, and therapeutic resistance; making it a viable therapeutic target. Here, we examined th …


Oncogene: Targeting farnesylation as a novel therapeutic approach in HRAS-mutant rhabdomyosarcoma (Vaseva)

April 25, 2022

Patience Odeniyide, Marielle E. Yohe, Kai Pollard, Angelina V. Vaseva,  Ana Calizo, Lindy Zhang, Fausto J. Rodriguez, John M. Gross, Amy N. Allen, Xiaolin Wan, Romel Somwar, Karisa C. Schreck, Linda Kessler, Jiawan Wang & Christine A. Pratilas Abst …


Gupta to Present at Cold Spring Harbor Meeting on Regulatory & Non-coding RNAs

April 24, 2022

Dr. Gupta’s virtual presentation at the Cold Spring Harbor meeting (May 17 – 21, 2022) is titled RNA binding to human METTL3-METTL14 restricts N6-deoxyadenosine methylation of DNA in vitro virtual talk. Read More


Clinical Cancer Research: The B7-H3-Targeting Antibody-Drug Conjugate m276-SL-PBD Is Potently Effective Against Pediatric Cancer Preclinical Solid Tumor Models (Kurmasheva & Houghton)

April 22, 2022

Nathan M Kendsersky # 1 2, Jarrett Lindsay # 1 2, E Anders Kolb 3, Malcolm A Smith 4, Beverly A Teicher 4, Stephen W Erickson 5, Eric J Earley 5, Yael P Mosse 1, Daniel Martinez 6, Jennifer Pogoriler 2 6, Kateryna Krytska 1, Khushbu Patel 1 7, David Gr …


Non-Coding RNA: Current Status of Epitranscriptomic Marks Affecting lncRNA Structures and Functions (Bishop Lab)

April 22, 2022

by Henry E. Miller 1,2,3ORCID, Mirolyuba Ilieva 4, Alexander J. R. Bishop 1,2,5ORCID and Shizuka Uchida 4, Non-Coding RNA 2022, 8(2), 23; https://doi.org/10.3390/ncrna8020023 Received: 1 March 2022 / Revised: 21 March 2022 / Accepted: 25 March 2022 / P …


American Society for Biochemistry and Molecular Biology: Sung takes over at San Antonio cancer institute

April 18, 2022