Greehey CCRI News & Events
Dr. Zhao Lai to Receive NCI R50 Funding
August 24, 2022The National Cancer Institute (NCI) has recently awarded an R50 Research Specialist Award to Dr. Zhao Lai, Associate Professor/Research, Director of the Next-Generation Sequencing Shared Resource (NGSSR) in the NCI-designated Mays Cancer Center (MCC). …
Business Wire: Lantern Pharma Reports Second Quarter 2022 Financial Results and Operational Highlights, Scientific Collaborations Updates (Houghton)
August 9, 2022During Childhood Cancer Awareness Month in September, Lantern will host a KOL webinar featuring Dr. Peter Houghton, Ph.D., a leading expert in childhood cancers at the Greehey Children’s Cancer Institute at the University of Texas San Antonio Health Sc …
Molecular Cancer Theraputics: Trastuzumab Deruxtecan, Antibody–Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium (Houghton, Kurmasheva)
August 3, 2022Pooja Hingorani Wendong Zhang; Zhongting Zhang; Zhaohui Xu; Wei-Lien Wang; Michael E. Roth Yifei Wang; Jonathan B. Gill Douglas J. Harrison; Beverly A. Teicher; Stephen W. Erickson Gregory Gatto; Edward A. Kolb Malcolm A. Smith Raushan T. Kurmasheva Pe …
Clinical Cancer Research: Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models (Houghton & Kurmasheva)
August 1, 2022Fuyang Li; Kathryn M. Bondra; Samson Ghilu; Adam Studebaker; Qianqian Liu Joel E. Michalek Mari Kogiso; Xiao-Nan Li John A. Kalapurakal; C. David James; Sandeep Burma; Raushan T. Kurmasheva Peter J. Houghton Abstract Purpose: We investigated why three …
Non-Coding RNA: Systematic Analysis of Long Non-Coding RNA Genes in Nonalcoholic Fatty Liver Disease (Bishop Lab)
July 27, 2022Mirolyuba Ilieva James Dao Henry E. Miller Jens Hedelund Madsen Alexander J. R. Bishop Sakari Kauppinen Shizuka Uchida Abstract The largest solid organ in humans, the liver, performs a variety of functions to sustain life. When damaged, cells in the …
Neuro – Oncology: ELF4 is a critical component of a miRNA-transcription factor network and is a bridge regulator of glioblastoma receptor signaling and lipid dynamics (Penalva Lab)
July 22, 2022Adam Kosti, Jennifer Chiou, Gabriela D A Guardia, Xiufen Lei, Henriette Balinda, Tesha Landry, Xiyuan Lu, Mei Qiao, Andrea Gilbert, Andrew Brenner … Show more Abstract Background The loss of neurogenic tumor suppressor microRNAs miR-124, miR-128, and …
Cell Reports Medicine: A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions (Wang)
July 21, 2022Cynthia M.Estrada-Zuniga18 Zi-MingCheng18 PurushothEthiraj18 QianjinGuo1 HectorGonzalez-Cantú1 ElainaAdderley2 HectorLopez1 Bethany N.Landry1 AbirZainal2 NeilAronin2 YanliDing3 XiaojingWang45 Ricardo C.T.Aguiar167 Patricia L.M.Dahia169 Hig …
International Journal of Molecular Sciences: Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist (Lai)
July 12, 2022Yi He 1,2, Salvador Alejo 1, Prabhakar Pitta Venkata 1, Jessica D. Johnson 1, Ilanna Loeffel 1, Uday P. Pratap 1, Yi Zou 3, Zhao Lai 3, Rajeshwar R. Tekmal 1,4, Edward R. Kost 1 and Gangadhara R. Sareddy 1,4,* Abstract Ovarian cancer (OCa) is the dead …
Nucleic Acids Research: Quality-controlled R-loop meta-analysis reveals the characteristics of R-loop consensus regions (Bishop Lab)
June 27, 2022Henry E Miller, Daniel Montemayor, Jebriel Abdul, Anna Vines, Simon A Levy, Stella R Hartono, Kumar Sharma, Bess Frost, Frédéric Chédin, Alexander J R Bishop Abstract R-loops are three-stranded nucleic acid structures formed from the hybridization of R …
Dr. Raushan Kurmasheva Received the CURE Childhood Cancer Award
June 24, 2022Abstract Atypical teratoid/rhabdoid tumors (AT/RT) of the brain and malignant rhabdoid tumors of the kidney (RTK) compose a group of highly malignant pediatric cancers known as malignant rhabdoid tumors (MRT). Both subtypes are characterized by the bia …