Automated Labcyte Echo Acoustic Dispenser

- Nanoliter-scale reagent dispenser
- Tipless transfer, resulting in dramatic cost savings
- Improved information about sample integrity and improved transfer quality through the measurement of DMSO or aqueous buffer levels.
- Elimination of RNAi or compound loss, cross-contamination, carryover, or leachates through non-contact transfer.
- Extend RNAi library life through miniaturization of assays.
- Greatly simplified assay development and dilution processes through the flexibility to transfer any volume of liquid from any well to any other well.
- Robotic integration with 80 microplate ambient storage units.
- Robotic integration with Agilent PlateLoc heat sealer, Brooks x-Peel desealer, and Agilent Barcode microplate labeler.
Vala Sciences IC200-KIC Automated High Content Imaging System.

- 5.54Mp sCMOS camera (100fps, full-frame)
- Plan APO 4X-60X objectives
- Rapid autofocus (<200ms)on every field
- Simple optical path
- High-resolution positioning (<100nm)
- Solid-state light engine with 5 discrete bands
- Filter set (DAPI, FITC, TRITC, Cy5)
- Environmental control (temperature, CO2, N2)
- Structured Illumination Microscopy module
- Integrated with a PreciseFlex 400 sample handler and a Liconic STX44 incubator for live cell experiments.
- Image analyses include cell counting, live/dead assays, subcellular localization, signal transduction pathway analysis, cell cycle, cell morphological analyses, cell migration
BMG Labtech Pherastar FS Multimode Plate Reader:

High Throughput Biochemical/Gene Expression/ Cell Viability Screens:
- Measurements of fluorescence intensity, fluorescence polarization, time-resolved fluorescence, TR-FRET, AlphaScreen, luminescence, UV/Vis Absorbance spectra
- Two reagent injectors for precise kinetic measurements: Capability for simultaneous injection of reagents and measurement, for highly precise kinetic measurements.
- Measurement modes: Top and Bottom reading, Endpoint and kinetic measurements, Simultaneous Dual Emission Measurements, Well Scanning.
A 0.1 mm resolution, automatic Z-height focusing optical stage that precisely focuses light onto the cell monolayer in cell-based assays. - Well, scanning that enables high-resolution cell layer detection, generating 3D topology maps for quantitative analyses of defined regions within a well in cell-based assays, significantly reducing inter-well variability.
- Sophisticated user-friendly analysis software is also available. In addition, this analysis software is freely available from BMG Labtech and thus allows users to analyze data on their own computers.
Dispensing and Plate Washing Capabilities for Biochemical and Cell-Based Assays
BioTek EL406 Dual Bulk Dispenser/Microplate Washer:
- Low-volume dispensing and plate washing.
- Specially designed for gentle washing of microplates containing living cells.
- Integrated with a BioStack microplate stacker.

General Lab Facilities for Assay Preparation
Cell culture incubators under normoxic and hypoxic conditions
Cell culture hoods
Microfuges and centrifuges
Liquid nitrogen cryopreservation
Refrigerators and freezers
