Cancer Knowledge Network: Neurocognitive Function, Sleep, and Fatigue in Female Childhood ALL Survivors
THE RESEARCH: Cancer: Impact of sleep, fatigue, and systemic inflammation on neurocognitive and behavioral outcomes in long-term survivors of childhood acute lymphoblastic leukemia. Researchers at St. Jude Children’s Research Hospital compiled cohorts of 35 male and 35 female survivors of childhood acute lymphoblastic leukemia with a mean age of 14.3 years and a mean years from diagnosis of 7.4 years. These cohorts were then evaluated with neurocognitive testing, behavioral ratings, reported sleep quality and fatigue symptoms. Additionally, serum markers of systemic inflammation were collected and evaluated. These included, interleukin 1-beta, interleukin-6, tumor necrosis factor alpha, and C-reactive protein.
Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to understanding its causes, and accelerate the translation of knowledge into novel therapies. Greehey CCRI strives to have a national and global impact on childhood cancer by discovering, developing, and disseminating new scientific knowledge. Our mission consists of three key areas — research, clinical, and education.
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