Texas Public Radio: San Antonio Scientists Uncover One Way The COVID-19 Virus Hides From The Immune System (Gupta)

Texas Public Radio | By Bonnie Petrie

Published June 7, 2021 at 3:47 PM CDT

Yogesh GuptaSan Antonio scientists have uncovered one of the disguises used by SARS-CoV-2 — the virus that causes COVID-19 — to hide from the immune system. They are metal ions that everyone has circulating in their body.

Dr. Yogesh Gupta is an assistant professor of biochemistry and structural biology at UT Health San Antonio and an investigator with its Greehey Children’s Cancer Research Institute. He said metal ions, like magnesium, manganese, and calcium, are often found in high concentrations in COVID-19 patients who are very sick.

“What has been observed in COVID-19 patients is that there is some correlation with the disease severity with the level of metal ions,” Gupta said.

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Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas — research, clinical, and education.

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