PR Stories

EurekAlert: Researchers (Houghton & Kurmasheva part of team who) identify surface protein as a new osteosarcoma therapeutic target for antibody-drug conjugates

April 13, 2021

Novel approach paves the way for a vast expansion in the number of drugs targeting osteosarcoma Abstract #LB008 HOUSTON — A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC) targeting surface protein MT1-MMP can act as a guided missile in eradicating osteosarcoma tumor cells […]

APPLICATIONS NOW BEING ACCEPTED: Greehey CCRI Donald G McEwen, Memorial Summer 2021 Undergraduate Research Program

April 6, 2021

Applications are now being accepted for the Greehey CCRI Undergraduate Summer Internship Program.   The purpose of the Greehey CCRI Undergraduate Summer Internship Program is to allow talented undergraduate students interested in a career in academic research the opportunity to spend approximately ten weeks during the summer conducting hypothesis-driven research in childhood cancer in one of the […]

Dr. Yogesh Gupta Delivers COVID Presentation to International Society for Stem Cell Research

February 26, 2021

    On February 25, 2021, Dr. Gupta delivered an invited talk at the International Society for Stem Cell Research COVID network meeting chaired by Hans-Willem Snoeck. MD, PhD (Columbia Univ.) and Todd McDevitt, PhD (Gladstone Inst., UCSF). At this meeting, Dr. Gupta presented his recent research on nonstructural proteins (nsps) of SARS-CoV-2. Some of […]

Argonne National Laboratory: Hide and Seek: Understanding How COVID-19 Evades Detection in a Human Cell (Gupta)

November 3, 2020

BY ANDRE SALLES |OCTOBER 29, 2020 Scientists using the Advanced Photon Source have discovered new insights into the ways the SARS-CoV-2 virus camouflages itself inside the human body. Scientists around the world have been working for months to identify and develop treatments that combat SARS-CoV-2, the virus that causes COVID-19. An important part of that process […]

ECancer Interview: Prospective validation of single mouse testing by the paediatric preclinical testing consortium (Houghton)

October 24, 2020

Dr. Peter Houghton speaks to ecancer about the prospective validation of single mouse testing by the pediatric preclinical testing consortium; a study that was presented at ENA 2020 this year. Dr. Houghton initially explains the rationale behind this study and talks about how it was tested that using a single mouse for studying drug efficacy […]

Cardiovascular Business: Chemotherapy could be damaging children’s heart cells, leading to problems later in life (Aune)

September 30, 2020

Undergoing chemotherapy can have a negative impact on the cells responsible for repairing heart damage, according to a new study published in PLOS One. This may explain why 20% of children treated with anthracyclines go on to experience heart failure later in life. “We don’t fully understand why some children who are exposed to anthracycline therapy […]

Ignatius Lab and Team “GCCRI Goes the Extra Mile” Organizing Local Alex’s Lemonade Stand “Million Mile” Virtual Event

September 3, 2020

It’s that time of year again where we tell everyone what we do. We also remember the children with cancer and know your research will make a difference. Join us again this year for The Million Mile this September to raise awareness for Childhood Cancer Awareness Month! Last year, we raised over $3,000 for Alex’s […]

Luiz O.F. Penalva PhD Awarded CPRIT Grant to Study New Glioblastoma (GBM) Regulator

August 20, 2020

PROJECT SUMMARY Glioblastoma (GBM) is the most common and most aggressive brain tumor type among adults with a 14 months average patient survival. Despite all genomic efforts in recent years, novel therapies based on GBM common mutations and alterations have been disappointing. To build an alternative route, we have been focusing on oncogenic RNA binding […]

Alexander Pertsemlidis, PhD Co-Awarded National Science Foundation Grant.

August 20, 2020

PI: Leonidas Bleris, PhD                       Co-PI: Alexander Pertsemlidis, PhD (UT Dallas)                                              (UT Health San Antonio) PROJECT SUMMARY Collaborative Research: Unraveling extracellular microRNA communication Overview: […]

Physician’s Weekly: PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models.

August 20, 2020

Although cancer is the leading cause of disease-related mortality in children, the relative rarity of pediatric cancers poses a significant challenge for developing novel therapeutics to further improve prognosis. Patient-derived xenograft (PDX) models, which are usually developed from high-risk tumors, are a useful platform to study molecular driver events, identify biomarkers and prioritize therapeutic agents.