Greehey Children's Cancer Research Institute
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September 10, 2026
What if we could stop an aggressive childhood brain tumor by disrupting the instructions it depends on to grow? At the Greehey Children’s Cancer Research Institute, the Penalva Lab, led by Luiz O.F. Penalva, PhD, studies RNA—the molecules that help cells decide when, where, and how genetic instructions are used. The lab is particularly interested [...]September 9, 2026
What if one of the biggest obstacles to treating a childhood cancer is that its main cancer-causing protein won’t hold still long enough to target it? That is part of the challenge facing researchers studying Ewing sarcoma, a rare and aggressive bone and soft-tissue cancer that primarily affects children and teenagers. At the Greehey Children's [...]September 8, 2026
Cancer cells are notorious rule-breakers. Sometimes, they even end up with the wrong number of chromosomes. At the Greehey Children's Cancer Research Institute, the Kitagawa Lab, led by Katsumi Kitagawa, Pharm.D., PhD, is investigating how mistakes involving our chromosomes may contribute to childhood cancer. Normally, when a cell divides, it must copy and distribute its chromosomes with remarkable [...]September 4, 2026
Why do some childhood cancers return after treatment—and why can they be so much harder to treat the second time? At the Greehey Children’s Cancer Research Institute, the Ignatius Lab, led by Myron Ignatius, PhD, is working to answer those questions by studying rhabdomyosarcoma, the most common soft-tissue sarcoma in children. A tumor isn’t simply [...]September 3, 2026
What if researchers could see the machinery inside a cancer cell closely enough to figure out exactly how to disrupt it? At the Greehey Children’s Cancer Research Institute, the Gupta Lab, led by Yogesh K. Gupta, M.Tech, PhD, studies the molecular structures and processes that help cancer cells survive and grow. The lab focuses on sarcomas and leukemias, [...]September 2, 2026
Cancer research generates an enormous amount of data. Hidden inside that data are clues that can help researchers better understand why childhood cancers develop, how they behave, and which treatments may work best. At the Greehey Children’s Cancer Research Institute, the Chen Lab, led by Yidong Chen, PhD, uses computational biology, bioinformatics and biostatistics to [...]September 1, 2026
Gregory J. Aune, MD, PhD, Surviving childhood cancer is the goal. But survival can come with consequences that last a lifetime. At the Greehey Children’s Cancer Research Institute, the Aune Lab, led by Gregory J. Aune, MD, PhD, studies the long-term health effects caused by the chemotherapy and radiation used to treat childhood cancer. Dr. [...]June 11, 2026
Researchers at the Greehey Children's Cancer Research Institute (Greehey CCRI) at UT Health San Antonio continue to push the boundaries of pediatric cancer research with the support of a new grant awarded by the Pediatric Cancer Foundation. Luiz O. Penalva, PhD, has received funding for his project, "RNA Therapeutics to Target Aggressive Medulloblastoma," which aims [...]June 2, 2026
REPOST: UT Health SA Newsroom Contact: Steven Lee, (210) 450-3823, lees22@uthscsa.edu Content provided by Jane Alvarez Hernandez Principal investigator: David Libich, PhD Associate professor in the Department of Biochemistry and Structural Biology in the Long School of Medicine and investigator with the Greehey Children’s Cancer Research Institute Award amount $250,000 Ewing sarcoma is a rare and aggressive cancer [...]
May 28, 2026
At the Greehey Children’s Cancer Research Institute (GCCRI), groundbreaking discoveries don’t just happen in theory—they are tested, refined, and brought closer to real-world impact through cutting-edge research platforms. One of the most powerful of these is the Xenograft & Cell Lines Core Facility, a cornerstone of GCCRI’s mission to accelerate new therapies for childhood cancer. [...]