Department of Defense Peer Reviewed Medical Research Program: SARS-CoV-2 Viral RNAs as Unique Biomarkers and Therapeutic Targets

Funding Agency: Department of Defense Peer-Reviewed Medical Research Program

Title: SARS-CoV-2 Viral RNAs as Unique Biomarkers and Therapeutic Targets

Status: Active

Period: 2/21-1/22

Role: Principal Investigator

Grant Detail:

Novel viruses, in particular RNA viruses, present a serious threat to global public health and disease control. Viral miRNAs (v-miRNAs) are known to play significant roles in the replication and propagation of viruses through both promotion of viral life cycle and suppression of host antiviral response. The proposed work will delineate the role of miRNAs in SARS-CoV-2 infection and will lay the groundwork for further preclinical evaluation.