PARP Inhibition: Elucidating Mechanisms of Resistance to Improve Therapy

Pilot Research Project        

Period: 05/01/2019 – 04/30/2020

Source: Mays Cancer Center, UT Health San Antonio

Title: PARP Inhibition: Elucidating Mechanisms of Resistance to Improve Therapy

Project goal: Investigate resistance of Ewing sarcoma cells to PARP inhibition using CRISPR-Cas9 approach.

Role: Principal Investigator


Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to understanding its causes, and accelerate the translation of knowledge into novel therapies. Greehey CCRI strives to have a national and global impact on childhood cancer by discovering, developing, and disseminating new scientific knowledge. Our mission consists of three key areas — research, clinical, and education.

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