Role of NRF2-ER and DNA damage stress response pathways in sensitivity of Ewing sarcoma cells to temozolomide and talazoparib.

Basic and Translational Science Award                                            

Source: GCCRI       

Period: 05/01/2017 – 04/30/2019                           

Title: Role of NRF2-ER and DNA damage stress response pathways in sensitivity of Ewing sarcoma cells to temozolomide and talazoparib.

Project Goal: Understand the role of ER homeostasis and DNA damage response pathway activation in Ewing sarcoma cells treated by temozolomide or talazoparib.

Role: Principal Investigator