University of Texas Health Science Center at San Antonio – UT Health San Antonio, “Non-Hodgkin Lymphoma: David Seitze”

December 12, 2018

UT Health San Antonio MD Anderson Cancer Center’s mission is to conquer cancer through research, prevention, and treatment—while offering world-class care close to home for patients in South Texas. How do ideas, collaboration, and dedication turn into hope for cancer patients? We’re how. You’re why. For more information about UT Health San Antonio, MD Anderson […]

YouTube: Children’s Cause, Challenges in Clinical Trial Design

September 18, 2018

CHILDHOOD CANCER HEARING LOSS AN EXTERNALLY-LED PATIENT-FOCUSED DRUG DEVELOPMENT WORKSHOP: CHEMOTHERAPY-INDUCED HEARING LOSS IN PEDIATRIC ONCOLOGY 3:25-3:35 Challenges in Clinical Trial Design in Chemotherapy-Induced Hearing Loss | Greg Aune, MD, PhD, Assistant Professor, UT Health San Antonio-Greehey Children’s Cancer Research Institute The half-day meeting follows the FDA model for externally-led PFDD meetings and will feature […]

FDA: The Voice of the Patient – Childhood Cancer Hearing Loss

September 13, 2018

Introduction: On September 13, 2018, four advocacy organizations – Children’s Cause for Cancer Advocacy, Children’s Brain Tumor Foundation, Mattie Miracle Cancer Foundation, and Momcology – hosted an Externally-Led Patient-Focused Drug Development (EL-PFDD) meeting to share with senior officials at the U.S. Food and Drug Administration and other chemotherapy-induced pediatric hearing loss stakeholders (e.g. families, caregivers, […]

Childhood Cancer Hearing Loss PFDD Meeting (Full Program)

September 13, 2018

The pediatric patient population with chemotherapy-induced hearing loss represents a segment of the cancer survivor community with a severe burden of disease with a great unmet medical need. An externally-led, FDA-approved Patient-Focused Drug Development (PFDD) meeting on September 13, 2018, near Washington, DC will explore these issues in-depth. The half-day meeting follows the FDA model […]

Journal of Clinical Oncology: Cardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention

July 20, 2018

Saro H. Armenian, Gregory T. Armstrong, Gregory Aune, Eric J. Chow, Matthew J. Ehrhardt, Bonnie Ky,  ABSTRACT Cardiovascular disease (CVD), which includes cardiomyopathy/heart failure, coronary artery disease, stroke, pericardial disease, arrhythmias, and valvular and vascular dysfunction, is a major concern for long-term survivors of childhood cancer. There is clear evidence of increased risk of CVD largely attributable to treatment exposures […]

Express-News: STAR Act is a victory for children with cancer

June 13, 2018

Express-News: STAR Act is a victory for children with cancer Published On: June 13, 2018 Shared by contributor By Gregory J. Aune, MD, PhD For the Express-News President Donald Trump’s signing of the Childhood Cancer Survivorship, Treatment, Access, and Research, or STAR, Act on Tuesday represents a significant legislative achievement in the ongoing battle to improve outcomes […]

Journal of Pediatric Hematology/Oncology: Aerobic Exercise During Early Murine Doxorubicin Exposure Mitigates Cardiac Toxicity

April 1, 2018

Wang, Fei PhD*; Iskra, Brian BS†; Kleinerman, Eugenie MD*; Alvarez-Florez, Claudia PhD*; Andrews, Thomas MSc†; Shaw, Angela MD*; Chandra, Joya PhD*; Schadler, Keri PhD*; Aune, Gregory J. MD, PhD†,‡ Abstract We report the cardioprotective effects of moderate aerobic exercise from parallel pediatric murine models of doxorubicin (Doxo) exposure in non–tumor-bearing immune-competent (NTB-IC) mice and tumor-bearing nude mice (TB-NM). […]