Clinical Breast Cancer: Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers

December 1, 2007

Tara M Friebel 1, Susan M Domchek, Susan L Neuhausen, Theresa Wagner, D Gareth Evans, Claudine Isaacs, Judy E Garber, Mary B Daly, Rosalind Eeles, Ellen Matloff, Gail Tomlinson, Henry T Lynch, Nadine Tung, Joanne L Blum, Jeffrey Weitzel, Wendy S Rubinstein, Patricia A Ganz, Fergus Couch, Timothy R Rebbeck Abstract Background: Women with BRCA1 or BRCA2 (BRCA1/2) mutations can reduce cancer incidence and mortality by using bilateral prophylactic oophorectomy (BPO) or bilateral prophylactic mastectomy […]