Siyuan Zheng, Ph.D.
Rank: Assistant Professor
Department: Epidemiology and Biostatistics
Our lab is located at the Greehey Cancer Research Institute (GCCRI). We use genomic and proteomic data to understand the mechanisms behind the initiation, progression, treatment responses of pediatric and adult cancers. Our research is focused to identifying aberrations in cancer, including single nucleotide variations, insertions, deletions, DNA and RNA structural rearrangements, DNA copy number alterations, that facilitate the various aspect of the cancer ecosystem.
We welcome motivated researchers and students with similar interest to join our team! We welcome motivated researchers and students with similar interest to join our team!
In this analysis we calculated telomere lengths for more than 10,000 human cancers from TCGA. We examined possible genetic and epigenetic mechanisms underlying telomerase reactivation and alternative lengthening of telomeres. Barthel et al. Nat Genet. 2017 Mar;49(3):349-357
We as a TCGA analysis working group comprehensively characterized the genomic and clinical profiles of 91 adrenocortical carcinomas, a rare but deadly endocrine cancer originating in the adrenal gland.Zheng et al. Cancer Cell. 2016 May 9;29(5):723-36.
Qilin Li, Ph.D.
Juechen (Jason) Yang, MBA
Gen. Program Analyst