Zheng Lab

Siyuan Zheng, Ph.D.

Rank: Assistant Professor
Department: Epidemiology and Biostatistics
Office: 3.100
Tel: 210-562-9028
Email: Zhengs3@uthscsa.edu

Our lab is located at the Greehey Cancer Research Institute (GCCRI). We use genomic and proteomic data to understand the mechanisms behind the initiation, progression, treatment responses of pediatric and adult cancers. Our research is focused to identifying aberrations in cancer, including single nucleotide variations, insertions, deletions, DNA and RNA structural rearrangements, DNA copy number alterations, that facilitate the various aspect of the cancer ecosystem.

We welcome motivated researchers and students with similar interest to join our team! We welcome motivated researchers and students with similar interest to join our team!

Lab Research

Latest Research

In this analysis we calculated telomere lengths for more than 10,000 human cancers from TCGA. We examined possible genetic and epigenetic mechanisms underlying telomerase reactivation and alternative lengthening of telomeres. Barthel et al. Nat Genet. 2017 Mar;49(3):349-357

We as a TCGA analysis working group comprehensively characterized the genomic and clinical profiles of 91 adrenocortical carcinomas, a rare but deadly endocrine cancer originating in the adrenal gland.Zheng et al. Cancer Cell. 2016 May 9;29(5):723-36.

Lab Staff

Qilin Li, Ph.D.
Postdoctoral Fellow

Yingli Lyu  
Postdoctoral Fellow

Nighat Noureen   
Postdoctoral Fellow

Juechen (Jason) Yang, MBA
Gen. Program Analyst