Nature Reviews – Molecular Cell Biology: Mechanisms and Disease Relevance of DNA Break Repair Pathway Choice (Sung Lab)
October 21, 2026Michelle L. Swift, Cody M. Rogers, Hardeep Kaur, Dipanjan Chowdhury & Patrick Sung Abstract Understanding what drives the choice between homologous recombination (HR) and non-homologous end joining (NHEJ) as the DNA double-strand break (DSB) repair …
Nature Communications: Saturation mutagenesis enables RAD51D clinical variant interpretation and identifies distinct biochemical functions (Sung/Olsen)
October 6, 2026Kristie E. Darrah, Shelby L. Hemker, Yashpal Rawal, Noah J. Goff, Phoebe S. Parker, Gayatri S. Ganesan, Caleb M. Stratton, Katherine G. Oppenheimer, Ella Roberts, Elena Glick, Nicole Banks, Arjun K. Kumar, Silvia Casadei, Matthew W. Snyder, Kara J. Mil …
Biomolecular NMR Assignments : The 1H, 15N and 13C backbone resonance assignments of an intrinsically disordered region (467–696) of breast cancer type 1 susceptibility protein (BRCA1) (Sung, Libich)
October 1, 2026Hoang H. Dinh, Angela M. Jasper, Antoine Baudin, Patrick Sung & David S. Libich The tumor suppressor protein breast cancer type 1 susceptibility protein (BRCA1) plays a central role in maintaining genome stability through its involvement in DNA dam …
Cell Reports: EWSR1::FLI1 promotes neocentromere formation in Ewing sarcoma cells (Kitagawa, Zheng, & Sung Labs)
September 30, 2026EWSR1::FLI1 promotes neocentromere formation in ewing sarcoma cells Risa Kitagawa1,2 ∙ Ediri E. Metitiri1,2 ∙ Bin Yu1,2 ∙ Changxian Shen1,2,6 ∙ Alexander J.R. Bishop1,3,5 ∙ Siyuan Zheng1,4 ∙ Peter J. Houghton1,2 ∙ Katsumi Kitagawa1,2,7 Highlights • EW …
🎗️ Childhood Cancer Awareness Month may be ending. The work is not.
September 29, 2026Throughout September, we’ve taken you behind the gold ribbon to show what childhood cancer research really looks like—from understanding cancer’s genetic blueprint to studying DNA damage, RNA biology, tumor behavior, and potential new treatments. At th …
Childhood Cancer Awareness Month: 🎗️ THE SCIENCE BEHIND THE GOLD RIBBON: THE HISTOLOGY CORE
September 28, 2026During Childhood Cancer Awareness Month, we’re taking you behind the scenes at the Greehey Children’s Cancer Research Institute to show how our researchers and Core & Research Services work together to advance childhood cancer research. Sometimes, …
Childhood Cancer Awareness Month🎗️:The Science Behind the Gold Ribbon: Xenograft & Cell-Lines Core
September 25, 2026From a Patient’s Tumor to a Model for Discovery A promising new cancer treatment can look great in a laboratory dish. But cancer is far more complicated inside a living body. Before a potential therapy can move closer to patients, researchers need to u …
Childhood Cancer Awareness Month: 🎗️ THE SCIENCE BEHIND THE GOLD RIBBON: THE TARGET DISCOVERY CORE
September 23, 2026Daohong Zhou, MD TIF Director What if researchers could switch off a gene inside a cancer cell and discover that the cancer could no longer survive without it? Finding vulnerabilities like that is part of the work the Target Discovery Core (TDC) at the …
Childhood Cancer Awareness Month: 🎗️ THE SCIENCE BEHIND THE GOLD RIBBON: THE GENOME SEQUENCING FACILITY
September 22, 2026Before researchers can understand what makes childhood cancer different, they must first see those differences. That is where the Genome Sequencing Facility (GSF) at the Greehey Children’s Cancer Research Institute plays a critical role. Cancer begins …
Childhood Cancer Awareness Month: 🎗️ THE SCIENCE BEHIND THE GOLD RIBBON: THE ZHENG LAB
September 21, 2026Every cancer leaves clues in its DNA. The challenge is finding the clues that matter. At the Greehey Children’s Cancer Research Institute, the Zheng Lab, led by Siyuan Zheng, PhD, uses cancer genomics, bioinformatics, and computational biology to searc …
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