Greehey CCRI News & Events Archive

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MedicalXpress – One Mouse at a Time: a New Approach to Testing Potential Drugs for Children’s Cancers (Houghton, Kurmasheva, PPTC)

October 22, 2020

by European Organisation for Research and Treatment of Cancer A team of researchers in the US and Australia have developed a way of testing potential drugs for children’s cancers so as to take account of the wide genetic diversity of these diseases. In …


Stand Up to Cancer: Alexander J. R. Bishop, DPhil to Lead One of Three Trans-Atlantic Teams to Study Hard-to-Treat Childhood Cancers

October 20, 2020

Published On: October 19, 2020 Shared by Rosanne Fohn SAN ANTONIO (Oct. 19, 2020) — Although COVID-19 has become the top health and research priority around the world, a child is still diagnosed with cancer every two minutes globally. To meet this urge …


Greehey CCRI Director, Peter J. Houghton, Ph.D. and Members of His Lab Co-Author Pediatric Blood & Cancer Paper

October 14, 2020

Radiation therapy and molecular‐targeted agents in preclinical testing for immunotherapy, brain tumors, and sarcomas: Opportunities and challenges Ralph Vatner, Charles D. James, Vythialingam Sathiaseelan, Kathryn M. Bondra, John A. Kalapurakal, Peter …


Pipette Gazette: Trevi Mancilla First Author Publication in PLOS One About The Significance Of Non-Cardiomyocyte Cells (Aune Lab)

September 30, 2020

Trevi Mancilla, a student in the South Texas Medical Scientist Training Program, has published a first-author publication in PLOS ONE. The title is “Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts.” Her mentor is Dr. Greg Aune. …


Cardiovascular Business: Chemotherapy could be damaging children’s heart cells, leading to problems later in life (Aune)

September 30, 2020

Undergoing chemotherapy can have a negative impact on the cells responsible for repairing heart damage, according to a new study published in PLOS One. This may explain why 20% of children treated with anthracyclines go on to experience heart failure l …


Medical Xpress: Childhood Chemo Alters Heart’s Caretaker Cells, Study Finds (Aune Lab)

September 30, 2020

by Will Sansom, UT Health San Antonio Cancer chemotherapy changes the function of cells that repair heart injury, researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered. Twenty percent of children …


Members of Lai Lab Co-Authors of Scientific Reports Paper

September 23, 2020

“Transcriptomic Sex Differences in Sensory Neuronal Populations of Mice” Abstract Many chronic pain conditions show sex differences in their epidemiology. This could be attributed to sex-dependent differential expression of genes (DEGs) involved in noc …


Physician’s Weekly: PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models.

September 20, 2020

Although cancer is the leading cause of disease-related mortality in children, the relative rarity of pediatric cancers poses a significant challenge for developing novel therapeutics to further improve prognosis. Patient-derived xenograft (PDX) models …


Raushan Kurmasheva, Ph.D, Part of Dmitri Ivanov, Ph.D., CPRIT Grant Team “Identifying and Optimizing Small Molecules for Drug Development.

September 8, 2020

SOURCE: UT Health San Antonio Newsroom “The following are the additional researchers and their awards: Dmitri Ivanov, Ph.D., associate professor of biochemistry and structural biology, will receive an Individual Investigator Research Award for Cancer i …


Nucleic Acids Research: “PCAT: an Integrated Portal for Genomic and Preclinical Testing Data of Pediatric Cancer Patient-Derived Xenograft Models” in Oxford Academic (multiple faculty and researchers)

September 8, 2020

Juechen Yang, Qilin Li, Nighat Noureen (Greehey CCRI, Zheng Lab), Yanbing Fang, Raushan Kurmasheva (Greehey CCRI, Kurmasheva Lab), Peter J Houghton (Greehey CCRI, Houghton Lab), Xiaojing Wang (Greehey CCRI, Wang Lab), Siyuan Zheng (Greehey CCRI, Zheng …