Zhao Lai, PhD to Receive $365K NIH Grant to Expand Integrated High-Performance Imaging-Based in-situ Spatial Profiling
July 8, 2025The 10x Genomics Xenium Analyzer is a cutting-edge, fully integrated platform for high-performance, imaging-based in situ spatial transcriptomics. It enables researchers to perform highly sensitive, high-throughput targeted gene expression profiling at …
Molecular Cancer Therapeutics: Targeting DDR2 for Treating Pancreatic Cancer (Rao Lab & Chen)
June 26, 2025Chris TP. Do Prabhakar Pitta Venkata Jack Y. Prochnau Deepika Singh Santosh Timilsina Panneerdoss Subbarayalu Daisy Medina Shahad Abdulsahib Saif Nirzhor Sajid Khan Guiming Li Srikanth R. Polusani Daohong Zhou Pei Wang Yidong Chen Ratna K. Vadlamudi M …
BioRxiv: Robust statistical assessment of Oncogenotype to Organotropism translation in xenografted zebrafish (Kurmasheva, et al)
June 24, 2025Abstract Organotropism results from the functional versatility of metastatic cancer cells to survive and proliferate in diverse microenvironments. This adaptivity can originate in clonal variation of the spreading tumor and is often empowered by epigen …
Daohong Zhou, MD, to Receive $2.4M CPRIT Award to Better Identify Therapeutic Targets and Develop Technologies to Target Hard-to-Treat Cancers.
June 23, 2025Develop transformative technologies that better target drug-resistant cancers Daohong Zhou, MD, tenured professor in the Department of Biochemistry and Structural Biology in the Joe R. and Teresa Lozano Long School of Medicine, received CPRIT’s academi …
Advanced Science: Biosecurity Primitive: Polymerase X-based Genetic Physical Unclonable Functions (Pertsemlidis)
June 18, 2025Zikun Zhou, Taek Kang, Jie Chen, Yesh Doctor, Jocelyn G Camposagrado, Yiorgos Makris, Alexander Pertsemlidis, Leonidas Bleris Abstract A Physical Unclonable Function (PUF) is a security primitive that exploits inherent variations in manufacturing proto …
Raushan Kurmasheva, PhD, was awarded the Translation to Cure (T2C) Award by the CURE Childhood Cancer foundation
June 16, 2025A cancer diagnosis is always devastating and is especially overwhelming when the patient is a child. This is why the CURE Childhood Cancer Foundation is on a mission to advance research that will bring an end to childhood cancers. The foundation priori …
Nature Communications: Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia (Bishop Lab)
June 3, 2025July Carolina Romero, Sonal S. Tonapi,Manish Parihar,Eva Loranc,Henry E. Miller,Liesl A. Lawrence,Nicklas Bassani,Daniel G. Robledo,Lin Cao,Jia Nie,Kairi Kanda,Aiola Stoja,Natalia Garcia,Aparna Gorthi,Brian J. Stoveken,Teresa W-M Fan,Teresa A. Cassel,S …
BioMolecular NMR Assignments: The 1H, 15N and 13C backbone resonance assignments of the N-terminal (1-149) domain of Serpine mRNA Binding Protein 1 (SERBP1) (Libich Lab)
May 30, 2025Antoine Baudin, Hoang H. Dinh, Xiaoping Xu & David S. Libich Abstract Serpine mRNA-Binding Protein 1 (SERBP1) is an RNA-binding protein implicated in diverse cellular functions, including translational regulation, tumor progression, and stress resp …
Science: CTC1-STN1-TEN1 controls DNA break repair pathway choice via DNA end resection blockade (Sung & Libich Labs)
May 23, 2025Cody M. Rogers, Hardeep Kaur, Michelle L. Swift , Vivek B. Raina , Shuo Zhou , Ajinkya S. Kawale Shahrez Syed , Korilynn G. Kelly , Angela M. Jasper , Sameer Salunkhe, Youngho Kwon , Jeffrey Wang, Aida Badamchi Shabestari, James M. Daley, Adam Sacks , …
PNAS: Phase separation of the oncogenic fusion protein EWS::FLI1 is modulated by its DNA-binding domain (Libich & Bishop Labs)
May 16, 2025Emily E. Selig Erich J. Sohn Aiola Stoja, Alma K. Moreno-Romero, Shivani Akula, Xiaoping Xu, Alexander J. R. Bishop, and David S. Libich Significance The oncogenic fusion protein, EWS::FLI1, responsible for more than 85% of Ewing sarcoma tumors, comb …
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