Greehey CCRI News & Events Archive

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EurekAlert: Researchers (Houghton & Kurmasheva part of team who) identify surface protein as a new osteosarcoma therapeutic target for antibody-drug conjugates

April 13, 2021

Novel approach paves the way for a vast expansion in the number of drugs targeting osteosarcoma Abstract #LB008 HOUSTON — A preclinical study led by researchers at The University of Texas MD Anderson Cancer Center shows an antibody-drug conjugate (ADC …


Cold Spring Harbor Molecular Case Studies: Bloom syndrome in a Mexican-American family with rhabdomyosarcoma: evidence of a Mexican founder mutation (Bishop, Chen, Tomlinson)

April 9, 2021

Erin H. Sybouts1,2,11, Adam D. Brown1,2,8,11, Maria G. Falcon-Cantrill3,9,11, Martha H. Thomas1,10, Thomas DeNapoli4,5, Julie Voeller5,6, Yidong Chen1,7, Gail E. Tomlinson1,3 and Alexander J.R. Bishop1,2 Abstract Bloom syndrome is a rare autosomal rece …


APPLICATIONS NOW BEING ACCEPTED: Greehey CCRI Donald G McEwen, Memorial Summer 2021 Undergraduate Research Program

April 6, 2021

Applications are now being accepted for the Greehey CCRI Undergraduate Summer Internship Program.   The purpose of the Greehey CCRI Undergraduate Summer Internship Program is to allow talented undergraduate students interested in a career in academic r …


Cancer Letters: COX-2 promotes mammary adipose tissue inflammation, local estrogen biosynthesis, and carcinogenesis in high-sugar/fat diet treated mice (Bishop)

April 1, 2021

Rosângela MayerGonçalvesa, Marina Delgoboa, Jonathan Paulo Agnesa, Raquel Nascimento das Nevesa, MarceloFalchettia, Tuany Casagrandea, Ana Paula Vargas Garciab, Thaynan Cunha Vieirab, Nauana Somensic, Maciel Alencar Bruxeld, Daniel Augusto Gasparin Bue …


Cancer Research: Deciphering the role of intestinal crypt cell populations in resistance to chemotherapy (Penalva Lab)

March 30, 2021

Carla Frau, Catherine Jamard, Gaspard Delpouve, Gabriela D. A. Guardia, Christelle Machon, Camilla Pilati, Clementine Le Neve, Pierre Laurent-Puig, Jérôme Guitton, Pedro A. F. Galante, Luiz O. Penalva, Jean-Noel Freund, Christelle de la Fouchardière an …


Development: The murine intestinal stem cells are highly sensitive to the modulation of the T3/TRα1-dependent pathway (Penalva Lab)

March 30, 2021

Matthias Godart, Carla Frau, Diana Farhat, Maria Virginia Giolito, Catherine Jamard, Clementine Le Nevé, Jean-Noel Freund, Luiz O. Penalva, Maria Sirakov, Michelina Plateroti Abstract The thyroid hormone T3 and its nuclear receptor TRα1 control gut dev …


MDPI: Musashi1 Contribution to Glioblastoma Development via Regulation of a Network of DNA Replication, Cell Cycle and Division Genes (Penalva Lab)

March 30, 2021

Mirella Baroni 1,†,  OrcID,Caihong Yi 1,2,†,  Saket Choudhary 3,†,  Xiufen Lei 1,  Adam Kosti 1,4,   Denise Grieshober 1,  Mitzli Velasco 1,  Mei Qiao 1,  Suzanne S. Burns 1,‡,  Patricia R. Araujo 1,  Talia DeLambre 1,  Mi Young Son 5,  Michelina Plate …


Cell Cycle: Regulation of DNA duplication by the mTOR signaling pathway (Houghton)

March 11, 2021

ABSTRACT Accurate and complete DNA replication and separation are essential for genetic information inheritance and organism maintenance. Errors in DNA duplication are the main source of genetic instability. Understanding DNA duplication regulation is …


Nighat Noureen, PhD, Awarded CPRIT Postdoctoral Training Award (Zheng Lab)

March 10, 2021

    Congratulations to Nighat Noureen, PhD, a postdoctoral fellow in the lab of Greehey CCRI principal investigator, Siyuan Zheng, PhD, on recently being awarded a CPRIT fellowship training grant. Dr. Noureen joined Dr. Zheng’s lab in June 20 …


Dr. Yogesh Gupta Delivers COVID Presentation to International Society for Stem Cell Research

February 26, 2021

    On February 25, 2021, Dr. Gupta delivered an invited talk at the International Society for Stem Cell Research COVID network meeting chaired by Hans-Willem Snoeck. MD, PhD (Columbia Univ.) and Todd McDevitt, PhD (Gladstone Inst., UCSF). At …


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