GCCRI &10x Genomics Presents: Spatial GEX Sample Prep Seminar (Xenium & Visium Applications)
February 6, 2026The Genome Sequencing Facility (GSF) at the Greehey Children’s Cancer Research Institute (GCCRI), serving as the Next Generation Sequencing Shared Resource (NGSSR) of the Mays Cancer Center, is pleased to invite you to a Spatial Transcriptomics Sample …
NGS User Group Holiday Gathering
December 2, 2025Dear NGS Community, The Greehey Children’s Cancer Research Institute (CCRI) Genome Sequencing Facility (GSF), the Next Generation Sequencing Shared Resource of the Mays Cancer Center, warmly invites you to our 2025 NGS User Group Holiday Party: 📅 Wedne …
Zhao Lai, PhD to Receive $365K NIH Grant to Expand Integrated High-Performance Imaging-Based in-situ Spatial Profiling
July 8, 2025The 10x Genomics Xenium Analyzer is a cutting-edge, fully integrated platform for high-performance, imaging-based in situ spatial transcriptomics. It enables researchers to perform highly sensitive, high-throughput targeted gene expression profiling at …
NPJ – Precision Oncology: Benchmarking mouse contamination removing protocols in patient-derived xenografts genomic profiling (Zheng, Wang, Kurmasheva, Houghton, Lai, & Chen Labs)
April 17, 2025Mukund Bhandari, Funan He, Anna Rogojina, Fuyang Li, Yi Zou, Jing Jiang, Zhao Lai, Peter Houghton, Raushan T. Kurmasheva, Yidong Chen, Xiaojing Wang & Siyuan Zheng Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. …
Pigment Cell & Melanoma: Segregation Between an Ornamental and a Disease Driver Gene Provides Insights Into Pigment Cell Regulation (Lai Lab)
September 25, 2024Erika Soria, Qiusheng Lu, Will Boswell, Kang Du, Yanting Xing, Mikki Boswell, Korri S. Weldon, Zhao Lai, Markita Savage, Manfred Schartl, Yuan Lu ABSTRACT Genetic interactions are adaptive within a species. Hybridization can disrupt such species-specif …
Journal of the National Cancer Institute: Integrative multi-omics characterization of hepatocellular carcinoma in Hispanic patients (Zheng, Chen & Lai Labs)
September 4, 2024Debodipta Das, PhD, Xiaojing Wang, PhD, Yu-Chiao Chiu, PhD, Hakim Bouamar, PhD, Francis E Sharkey, MD, Jorge E Lopera, MD, Zhao Lai, PhD, Susan T Weintraub, PhD, Xianlin Han, PhD, Yi Zou, MS, Hung-I H Chen, PhD, Carla R Zeballos Torrez, MD, PhD, Xiang …
MDPI Cancers: Synergistic Antitumor Activity of Talazoparib and Temozolomide in Malignant Rhabdoid Tumors (Kurmasheva, Lai, & Chen)
June 18, 2024Elena Mironova, Sebastian Molinas, Vanessa Del Pozo, Abhik M. Bandyopadhyay, Zhao Lai, Dias Kurmashev, Eric L. Schneider, Daniel V. Santi, Yidong Chen, Raushan T. Kurmasheva Simple Summary Mutation of the SMARCB1 gene can cause one …
Precision Oncology: Pharmacological inhibition of the LIF/LIFR autocrine loop reveals vulnerability of ovarian cancer cells to ferroptosis (Chen, Lai, Rao, et al)
June 17, 2024Behnam Ebrahimi, Suryavathi Viswanadhapalli, Uday P. Pratap, Gopalam Rahul, Xue Yang, Prabhakar Pitta Venkata, Viktor Drel, Bindu Santhamma, Swapna Konda, Xiaonan Li, Alondra Lee Rodriguez Sanchez, Hui Yan, Gangadhara R. Sareddy, Z …
Scientific Reports: Associations of tissue damage induced inflammatory plasticity in masseter muscle with the resolution of chronic myalgia (Lai)
January 4, 2024Abstract Gene plasticity during myogenous temporomandibular disorder (TMDM) development is largely unknown. TMDM could be modeled by intramuscular inflammation or tissue damage. To model inflammation induced TMDM we injected complete Freund’s adjuvant …
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