Genome Biology: The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation.
August 20, 2020Background RNA-binding proteins (RBPs) function as master regulators of gene expression. Alterations in RBP expression and function are often observed in cancer and influence critical pathways implicated in tumor initiation and growth. Identification a …
Alexander Pertsemlidis, PhD Co-Awarded National Science Foundation Grant.
August 20, 2020PI: Leonidas Bleris, PhD Co-PI: Alexander Pertsemlidis, PhD (UT Dallas) (UT Health San Antonio) PROJECT SUMMARY Collaborative Research: Unraveling extracellular microRNA communication O …
Physician’s Weekly: PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models.
August 20, 2020Although cancer is the leading cause of disease-related mortality in children, the relative rarity of pediatric cancers poses a significant challenge for developing novel therapeutics to further improve prognosis. Patient-derived xenograft (PDX) models …
Luiz O.F. Penalva PhD Awarded CPRIT Grant to Study Glioblastoma (GBM)
August 20, 2020PROJECT SUMMARY Glioblastoma (GBM) is the most common and most aggressive brain tumor type among adults with a 14 months average patient survival. Despite all genomic efforts in recent years, novel therapies based on GBM common mutations and alteration …
Cellular and Molecular Bioengineering: Scaffold Architecture and Matrix Strain Modulate Mesenchymal Cell and Microvascular Growth and Development in a Time Dependent Manner
August 18, 20202020 CMBE Young Innovators issue Gennifer Chiou, Elysa Jui, Allison C. Rhea, Aparna Gorthi, Solaleh Miar, Francisca M. Acosta, Cynthia Perez, Yasir Suhail, Kshitiz, Yidong Chen, Joo L. Ong, Rena Bizios, Christopher Rathbone & Teja Guda Abstract Bac …
PIPETTE GAZETTE: CSA Shoutout to Graduating Student Pooja Yadav (Rao Lab)
August 11, 2020Congratulations to one of our CSA graduate students Pooja Yadav, M.S. (Cancer Biology discipline) who successfully defended her PhD dissertation on June 25!
Genome Biology: The RNA-binding protein SERBP1 functions as a novel oncogenic factor in glioblastoma by bridging cancer metabolism and epigenetic regulation (Bishop & Penalva Labs)
August 6, 2020Adam Kosti 1 2, Patricia Rosa de Araujo 1 2, Wei-Qing Li 1 3, Gabriela D A Guardia 4, Jennifer Chiou 5, Caihong Yi 1, Debashish Ray 6, Fabiana Meliso 4, Yi-Ming Li 3, Talia Delambre 1, Mei Qiao 1, Suzanne S Burns 1, Franziska K Lorbeer 1, Fanny Georgi …
Health 24: How the coronavirus infects: It can make itself unrecognisable to cells in the body
August 5, 2020Like a thief in the night, Covid-19 can disguise itself to easily enter and infect cells in the human body. A new research study details what cells are more susceptible to the coronavirus. SARS-CoV-2 can mimic the proteins of a human cell to evade dete …
PNAS: Necroptosis-based CRISPR knockout screen reveals Neuropilin-1 as a critical host factor for early stages of murine cytomegalovirus infection
August 3, 2020Rebecca K Lane 1, Hongyan Guo 2, Amanda D Fisher 1, Jonathan Diep 3, Zhao Lai 4 5, Yidong Chen 5 6, Jason W Upton 7, Jan Carette 3, Edward S Mocarski 8, William J Kaiser 9 Abstract Herpesviruses are ubiquitous human pathogens that cause a wide range of …