Dr. Yogesh Gupta Delivers COVID Presentation to International Society for Stem Cell Research

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International Society for Stem Cell Research

 

 

Yogesh Gupta, PhD

On February 25, 2021, Dr. Yogesh Gupta delivered an invited talk at the International Society for Stem Cell Research COVID network meeting chaired by Hans-Willem Snoeck. MD, PhD (Columbia Univ.) and Todd McDevitt, PhD (Gladstone Inst., UCSF). At this meeting, Dr. Gupta presented his recent research on nonstructural proteins (nsps) of SARS-CoV-2. Some of these enzymes chemically modify the genetic code (the messenger RNA) of the virus in order to protect it from degradation and to subvert the innate immune response inside the host cells. His laboratory has been investigating three-dimensional structures of key viral enzymes and their cellular partners. The atomic-level details derived from his studies will provide important insights into the mechanisms that enable the virus to grow inside the human body and will be crucial for devising innovative strategies for drug development for the treatment of COVID-19 and emerging coronaviral infections.

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Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of its causes, and accelerate the translation of knowledge into novel therapies. Through discovery, development, and dissemination of new scientific knowledge, Greehey CCRI strives to have a national and global impact on childhood cancer. Our mission consists of three key areas — research, clinical, and education.

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