Oncogene: Knock-out of Hopx disrupts stemness and quiescence of hematopoietic stem cells in mice (Chen Lab)
June 12, 2020Chien-Chin Lin, Chi-Yuan Yao, Yueh-Chwen Hsu, Hsin-An Hou, Chang-Tsu Yuan, Yi-Hung Li, Chein-Jun Kao, Po-Han Chuang, Yu-Chiao Chiu, Yidong Chen, Wen-Chien Chou & Hwei-Fang Tien Abstract HOPX is a stem cell marker in hair follicles and intestines. I …
Jove: Mass Spectrometry Analysis to Identify Ubiquitylation of EYFP-tagged CENP-A (EYFP-CENP-A)
June 10, 2020Yohei Niikura*1, Lei Fang*2, Risa Kitagawa*3, Peizhao Li1, Yao Xi1, Ju You1, Yan Guo2, Katsumi Kitagawa3 Summary CENP-A ubiquitylation is an important requirement for CENP-A deposition at the centromere, inherited through dimerization between cell divi …
Clinical Cancer Research: Evaluation of Eribulin Combined with Irinotecan for Treatment of Pediatric Cancer Xenografts
June 1, 2020Andrew J. Robles, Raushan T. Kurmasheva, Abhik Bandyopadhyay, Doris A. Phelps, Stephen W. Erickson, Zhao Lai, Dias Kurmashev, Yidong Chen, Malcom A. Smith, and Peter J. Houghton Abstract Purpose: Vincristine combined with camptothecin derivatives showe …
Springer Link: Genetic markers for treatment-related pancreatitis in a cohort of Hispanic children with acute lymphoblastic leukemia
May 24, 2020Allison C. Grimes, Yidong Chen, Hima Bansal, Christine Aguilar, Luz Perez Prado, Gerardo Quezada, Jaime Estrada & Gail E. Tomlinson Abstract Purpose Treatment-related pancreatitis (TRP) is a serious complication occurring in children with acute lym …
Kunal Baxi, PhD to receive Translational Science Training (TST) TL1 award. (Ignatius Lab)
May 18, 2020The Greehey Children’s Cancer Research Institute, UT Health San Antonio wishes to congratulate Kunal Baxi, PhD, from the lab of Principal Investigator, Myron Ignatius, PhD. on receiving the UT Health San Antonio, Translational Science Training (TST) TL …
Nature Cell Biology: Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance
May 18, 2020Mingjun Bi 1, Zhao Zhang 1, Yi-Zhou Jiang 2, Pengya Xue 1, Hu Wang 1, Zhao Lai 1, Xiaoyong Fu 3, Carmine De Angelis 3, Yue Gong 2, Zhen Gao 4, Jianhua Ruan 1 4, Victor X Jin 1, Elisabetta Marangoni 5, Elodie Montaudon 5, Christopher K Glass 6, Wei Li 7 …
Trauma & Acute Care Surgery: The gut microbiome distinguishes mortality in trauma patients upon admission to the emergency department
May 1, 2020Burmeister, David M. PhD; Johnson, Taylor R. BS; Lai, Zhao PhD; Scroggins, Shannon R. MS; DeRosa, Mark CRT; Jonas, Rachelle B. RN; Zhu, Caroline BS; Scherer, Elizabeth MD, MPH; Stewart, Ronald M. MD, FACS; Schwacha, Martin G. PhD; Jenkins, Donald H. MD …
Cell Chemical Biology: MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
May 1, 2020ZhiJun Qiu 1, An-Ping Lin 1, Shoulei Jiang 1, Sara M Elkashef 1, Jamie Myers 1, Subramanya Srikantan 2, Binu Sasi 1, John Z Cao 3, Lucy A Godley 3, Dinesh Rakheja 4, Yingli Lyu 5, Siyuan Zheng 6, Muniswamy Madesh 2, Yuzuru Shiio 7, Patricia L M Dahia 1 …
Nucleic Acids Research: Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA (Bishop)
April 30, 2020Hai Pan, Miao Jin, Ashwin Ghadiyaram, Parminder Kaur, Henry E Miller, Hai Minh Ta, Ming Liu, Yanlin Fan, Chelsea Mahn, Aparna Gorthi … Show more Abstract Cohesin SA1 (STAG1) and SA2 (STAG2) are key components of the cohesin complex. Previous studie …
MDPI Cancers Magazine – Reconstruction of Ewing Sarcoma Developmental Context from Mass-Scale Transcriptomics Reveals Characteristics of EWSR1-FLI1 Permissibility (Bishop Lab)
April 16, 2020by Henry E. Miller 1,2, Aparna Gorthi 1,2, Nicklas Bassani 2, Liesl A. Lawrence 1,2, Brian S. Iskra 1,2 and Alexander J. R. Bishop 1,2,* This study aims at defining the features of the cell of origin for Ewing sarcoma through comparative bioinformatic …