Greehey CCRI News & Events Archive
Proteome Science: Fully automated protein complex prediction based on topological similarity and community structure
November 7, 2013Chengwei Lei, Saleh Tamim, Alexander JR Bishop & Jianhua Ruan Abstract To understand the function of protein complexes and their association with biological processes, a lot of studies have been done towards analyzing the protein-protein interact …
DNA Repair: Induction of homologous recombination following in utero exposure to DNA-damaging agents
November 1, 2013Bijal Kariaab, Jo Ann Martinez, Alexander J.R.Bishop Abstract Much of our understanding of homologous recombination, as well as the development of the working models for these processes, has been derived from extensive work in model organisms, such as …
EURASIP Journal on Bioinformatics and Systems Biology: Identification of genomic functional hotspots with copy number alteration in liver cancer
October 25, 2013Tzu-Hung Hsiao, Hung-I Harry Chen, Stephanie Roessler, Xin Wei Wang & Yidong Chen Abstract Copy number alterations (CNAs) can be observed in most cancer patients. Several oncogenes and tumor suppressor genes with CNAs have been identified in differ …
Cancer Epidemiology Biomarkers & Preventinon: Parental tobacco and alcohol use and risk of hepatoblastoma in offspring: a report from the children’s oncology group
October 15, 2013Kimberly J Johnson 1, Katherine S Williams, Julie A Ross, Mark D Krailo, Gail E Tomlinson, Marcio H Malogolowkin, James H Feusner, Logan G Spector Abstract Background: Hepatoblastoma is a rare pediatric liver tumor that has significantly increased in i …
Taylor Francis: A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel
September 30, 2013Liqin Du, Robert Borkowski, Zhenze Zhao, Xiuye Ma, Xiaojie Yu, Xian-Jin Xie &Alexander Pertsemlidis microRNAs (miRNAs) are small RNAs endogenously expressed in multiple organisms that regulate gene expression largely by decreasing levels of target …
Frontiers in Psychiatry: The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers
September 23, 2013Jason D Robinson 1, Francesco Versace, Cho Y Lam, Jennifer A Minnix, Jeffrey M Engelmann, Yong Cui, Maher Karam-Hage, Sanjay S Shete, Gail E Tomlinson, Tina T-L Chen, David W Wetter, Charles E Green, Paul M Cinciripini Abstract A compromised brain rewa …
Echocardiography: Cardiac Assessment in Pediatric Mice: Strain Analysis as a Diagnostic Measurement
September 19, 2013Thomas G. Andrews M.Sc., Merry L. Lindsey PhD, Richard A. Lange MD, M.B.A, Gregory J. Aune MD, PhD Abstract Echocardiography is a robust tool for assessing cardiac function in both humans and laboratory animals. Conventional echocardiographic measurem …
Oncogene:miR-93-directed downregulation of DAB2 defines a novel oncogenic pathway in lung cancer
September 16, 2013L Du, Z Zhao, X Ma, T-H Hsiao, Y Chen, E Young, M Suraokar, I Wistuba, J D Minna & A Pertsemlidis Abstract The disabled homolog 2 (DAB2) gene was recently identified as a tumor suppressor gene with its expression downregulated in multiple cancer ty …
Modern Pathology: Towards an international pediatric liver tumor consensus classification: proceedings of the Los Angeles COG liver tumors symposium
September 6, 2013Dolores López-Terrada 1, Rita Alaggio 2, Maria T de Dávila 3, Piotr Czauderna 4, Eiso Hiyama 5, Howard Katzenstein 6, Ivo Leuschner 7, Marcio Malogolowkin 8, Rebecka Meyers 9, Sarangarajan Ranganathan 10, Yukichi Tanaka 11, Gail Tomlinson 12, Monique F …
Oncogene: Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer
August 26, 2013S S Roy 1, V K Gonugunta 1, A Bandyopadhyay 2, M K Rao 3, G J Goodall 4, L-Z Sun 3, R R Tekmal 5, R K Vadlamudi 5 Abstract Tumor metastasis is the leading cause of death among breast cancer patients. PELP1 (proline, glutamic acid, and leucine-rich prot …