UT Health SA Newsroom: Greehey researcher receives UT System’s Rising STARs award
February 26, 2019Siyuan Zheng, PhD, assistant professor in the Department of Epidemiology and Biostatistics in the Long School of Medicine, has received a Rising STARs Award from the UT System. The award for early-career investigators comes with a $250,000 grant.
PNAS: Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR
February 26, 2019Samuel A. Kotler, Vitali Tugarinov, Thomas Schmidt, Alberto Ceccon, David S. Libich, Rodolfo Ghirlando, Charles D. Schwieters, and G. Marius Clore Abstract The N-terminal region of the huntingtin protein, encoded by exon-1, comprises an amphiphilic dom …
San Antonio Business Journal: SA gets small share of more than $90M in state cancer research money
February 22, 2019The Cancer Prevention and Research Institute of Texas has awarded 54 new academic research, prevention and product development grants totaling nearly $96 million. San Antonio’s cut is $3 million. All three Alamo City grants will support research at UT …
UT Health Newsroom: UT Health San Antonio researchers awarded $3 million for cancer studies
February 22, 2019Ewing sarcoma research Yuzuru Shiio, MD, PhD, of the Greehey Children’s Cancer Research Institute at UT Health San Antonio, was awarded $1.2 million to further studies of Ewing sarcoma, a pediatric bone and soft tissue cancer. The median age of Ewing s …
Pharmacy Times: Chemotherapies May Have Varying Long-Term Cardiovascular Risk
February 6, 2019By studying the outcomes of more than 28,000 long-term childhood cancer survivors in the United States and Europe, researchers found that exposure to different anthracyclines results in variable long-term cardiovascular risk.
BMC Genomics: CeL-ID: cell line identification using RNA-seq data
February 4, 2019Tabrez A. Mohammad, Yun S. Tsai, Safwa Ameer, Hung-I Harry Chen, Yu-Chiao Chiu & Yidong Chen Abstract Background Cell lines form the cornerstone of cell-based experimentation studies into understanding the underlying mechanisms of normal and diseas …
Journal of Oral Pathology & Medicine: The novel capsazepine analog, CIDD‐99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1‐independent induction of ER stress, mitochondrial dysfunction, and apoptosis
February 3, 2019Jorge J. De La Chapa, Prajjal K. Singha, Kristen K. Self, McKay L. Sallaway, Stanton F. McHardy, Matthew J. Hart, Howard Stan McGuff, Matthew C. Valdez Francisco Ruiz II, Srikanth R. Polusani, Cara B. Gonzales Abstract Background Oral squamous cell car …
Oncology Learning Network: Podcast – Daunorubicin Decreases Long-Term Cardiomyopathy Risk in Cancer Survivors
January 31, 2019In an interview with Oncology Learning Network, Gregory J. Aune, MD, Assistant Professor of Pediatrics at UT Health San Antonio and Greehey Children’s Cancer Research Institute, discussed his team’s findings from a multicenter study evaluating the long …
Drug Discovery & Development: Do All Chemotherapies Have Equal Long-Term Heart Risk?
January 31, 2019Gregory Aune, MD, PhD, of UT Health San Antonio, served on a team that found different chemotherapy drugs used to treat children with cancer appear to have different risks long term for cardiomyopathy (abnormal heart muscle with impaired function). The …
BMC Medical Genomics: Predicting drug response of tumors from integrated genomic profiles by deep neural networks
January 31, 2019Yu-Chiao Chiu, Hung-I Harry Chen, Tinghe Zhang, Songyao Zhang, Aparna Gorthi, Li-Ju Wang, Yufei Huang & Yidong Chen Abstract Background The study of high-throughput genomic profiles from a pharmacogenomics viewpoint has provided unprecedented insig …