NPJ – Precision Oncology: Benchmarking mouse contamination removing protocols in patient-derived xenografts genomic profiling (Zheng, Wang, Kurmasheva, Houghton, Lai, & Chen Labs)
April 17, 2025Mukund Bhandari, Funan He, Anna Rogojina, Fuyang Li, Yi Zou, Jing Jiang, Zhao Lai, Peter Houghton, Raushan T. Kurmasheva, Yidong Chen, Xiaojing Wang & Siyuan Zheng Abstract Patient-derived xenograft (PDX) models are widely used in cancer research. …
Kurmasheva Lab is Featured in CPRIT Annual Report
February 6, 2025Doctors diagnose nearly 1,200 Texans under 20 years of age with cancer every year. Despite intensive genotoxic therapy, nearly 20% of these children will die from their cancer. Those who survive face a lifetime of potential toxicities due to their ther …
Pharmacology & Therapeutics: Lessons learned from 20 years of preclinical testing in pediatric cancers (Houghton, Kurmasheva)
November 11, 2024Malcolm A. Smith a, Peter J. Houghton b, Richard B. Lock c, John M. Maris d, Richard Gorlick e, Raushan T. Kurmasheva b, Xiao-Nan Li f, Beverly A. Teicher a, Jeffrey H. Chuang g, Filemon S. Dela Cruz h, Michael A. Dyer i, Andrew L. Kung h, Michael W. L …
MDPI Cancers: Synergistic Antitumor Activity of Talazoparib and Temozolomide in Malignant Rhabdoid Tumors (Kurmasheva, Lai, & Chen)
June 18, 2024Elena Mironova, Sebastian Molinas, Vanessa Del Pozo, Abhik M. Bandyopadhyay, Zhao Lai, Dias Kurmashev, Eric L. Schneider, Daniel V. Santi, Yidong Chen, Raushan T. Kurmasheva Simple Summary Mutation of the SMARCB1 gene can cause one …
IScience: Comprehensive Characterization of Patient-Derived Xenograft Models of Pediatric Leukemia (Houghton, Grimes, Lai, Chen, Zheng, Kurmasheva, & Tomlinson Labs)
December 6, 2023Anna Rogojina 1 12, Laura, J. Klesse 2 3 4 12, Erin Butler 2 3 4 12, Jiwoong Kim 5, He Zhang 5, Xue Xiao 5, Lei Guo 5, Qinbo Zhou 5, Taylor Hartshorne 2, Dawn Garcia 1, Korri Weldon 1, Trevor Holland 1, Abhik Bandyopadhyay 1, Luz Perez Prado 1, Shidan …
Nature Communications: Genomic profiling of subcutaneous patient-derived xenografts reveals immune constraints on tumor evolution in childhood solid cancer (Zheng, Grimes, Lai, Chen, Wang, Tomlinson, Houghton, & Kurmasheva Labs)
November 27, 2023Funan He, Abhik M. Bandyopadhyay, Laura J. Klesse, Anna Rogojina, Sang H. Chun, Erin Butler, Taylor Hartshorne, Trevor Holland, Dawn Garcia, Korri Weldon, Luz-Nereida Perez Prado, Anne-Marie Langevin, Allison C. Grimes, Aaron Sugalski, Shafqat Shah, Ch …
Clinical Cancer Research: Surface and Global Proteome Analyses Identify ENPP1 and Other Surface Proteins as Actionable Immunotherapeutic Targets in Ewing Sarcoma (Kurmasheva)
October 18, 2023Brian Mooney Gian Luca Negri Taras Shyp Alberto Delaidelli Hai-Feng Zhang Sandra E. Spencer Miko Amber K. Weiner Alexander B. Radaoui Rawan Shraim Michael M. Lizardo Christopher S. Hughes Amy Li Melanie Rouleau Wei Li Dimiter S. Dimitrov Raushan T. Kur …
UT Health San Antonio gears up to fight childhood cancer, thanks to Hyundai Hope on Wheels® grants
September 26, 2023Posted on September 26, 2023 at 10:40 am.Shared by Eileen Teves Contacts: Monica Taylor, 210-450-8970, taylorm1@uthscsa.edu, Eileen Teves, 210-450-7239, tevese@uthscsa.edu SAN ANTONIO – Children with cancer were joined by their families as they dipped …
Molecular Cancer Theraputics: Trastuzumab Deruxtecan, Antibody–Drug Conjugate Targeting HER2, Is Effective in Pediatric Malignancies: A Report by the Pediatric Preclinical Testing Consortium (Houghton, Kurmasheva)
August 3, 2022Pooja Hingorani Wendong Zhang; Zhongting Zhang; Zhaohui Xu; Wei-Lien Wang; Michael E. Roth Yifei Wang; Jonathan B. Gill Douglas J. Harrison; Beverly A. Teicher; Stephen W. Erickson Gregory Gatto; Edward A. Kolb Malcolm A. Smith Raushan T. Kurmasheva Pe …
Clinical Cancer Research: Regulation of TORC1 by MAPK Signaling Determines Sensitivity and Acquired Resistance to Trametinib in Pediatric BRAFV600E Brain Tumor Models (Houghton & Kurmasheva)
August 1, 2022Fuyang Li; Kathryn M. Bondra; Samson Ghilu; Adam Studebaker; Qianqian Liu Joel E. Michalek Mari Kogiso; Xiao-Nan Li John A. Kalapurakal; C. David James; Sandeep Burma; Raushan T. Kurmasheva Peter J. Houghton Abstract Purpose: We investigated why three …
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