Greehey CCRI Archives

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ASM Journals: GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Cellular Transformation (Lai)

January 5, 2022

Shan Wei, Songjian Lu, Lifan Liang, Xian Wang, Wan Li, Tingting Li, Luping Chen, , Enguo Ju, Xinquan Zhang, Zhao Lai, Yufei Huang, Xinghua Lu, Shou-Jiang Gao  ABSTRACT Infection by Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally associated w …


MSN: Using Next Generation Sequencing, the Greehey CCRI bioinformatics team is helping determine COVID19 strains (Chen, Lai, Zheng, Wang Labs)

December 17, 2021

“Since the coronavirus pandemic began almost two years ago there have been over a dozen strains of the virus. Here at UT Health San Antonio, they have a lab which differentiates between each of the strains in an effort to save lives. UT Health San Anto …


Hepatology Communications: Dissecting the Balance Between Metabolic and Oncogenic Functions of Astrocyte-Elevated Gene-1/Metadherin (Lai Lab)

November 9, 2021

Yetirajam Rajesh, Saranya Chidambaranathan Reghupaty, Rachel G. Mendoza, Debashri Manna, Indranil Banerjee, Mark A. Subler, Korri Weldon, Zhao Lai, Shah Giashuddin, Paul B. Fisher, Arun J. Sanyal, Rebecca K. Martin, Mikhail G. Dozmorov, Jolene J. Windl …


Cancer Letters: KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer (Lai & Chen Labs)

October 28, 2021

Prabhakar PittaVenkataa1 YihongChenab1 SalvadorAlejoa YiHeab Bridgitte E.Palaciosa IlannaLoeffela JunhaoLiuacUday P.Pratapa GabrielleGraya Sureshkumar MulampurathAchuthan Pillaia YiZoud ZhaoLaideT akayoshiSuzukif SuryavathiViswanadhapallia SrinathPalak …


Journal of Virology: MULTIPLEXED SIV-SPECIFIC PAIRED RNA-GUIDED CAS9 NICKASES INACTIVATE PROVIRAL DNA (Lai)

September 23, 2021

Authors: Lisa M Smith, Jason T. Ladner, Vida L. Hodara, Laura M. Parodi, R. Alan Harris, Jessica E. Callery, Zhao Lai, Yi Zou, Muthuswamy Raveedran, Jeffrey Rogers, and Luis D. Giavedoni Abstract Human and simian immunodeficiency virus infections estab …


Journal of Trauma & Acute Care Surgery: Whole Blood Resuscitation Restores Intestinal Perfusion and Influences Gut Microbiome Diversity (Lai)

August 24, 2021

Yracheta, Jaclyn MD1; Muraoka, Wayne PhD2; Wu, Xiaowu MD2; Burmeister, David PhD3; Darlington, Daniel PhD2; Zhao, David MD2; Lai, Zhao PhD4; Scroggins, Shannon MS1; Cap, Andrew P. MD, PhD2; Bynum, James PhD2; Nicholson, Susannah E. MD1,2 Abstract Objec …


MSystems: Identification of a GrgA-Euo-HrcA Transcriptional Regulatory Network in Chlamydia (Lai Lab)

August 4, 2021

Wurihan Wurihan , Yi Zou, Alec M. Weber, Korri Weldon, Yehong Huang, Xiaofeng Bao, Chengsheng Zhu, Xiang Wu, Yaqun Wang, Zhao Lai, and Huizhou Fan  ABSTRACT Chlamydia trachomatis is an obligate intracellular bacterium whose unique developmental cycle c …


Greehey CCRI’s Genomic Sequencing Facility to Receive $600,000 NIH Grant to upgrade genomic sequencing capabilities (Lai Lab).

June 15, 2021

Dr. Zhao Lai, Director of the Genomic Sequencing Facility (GSF) at the Greehey Children’s Cancer Research Institute (Greehey CCRI) at UT Health San Antonio (UTHSA), has been awarded a $600,000 NIH grant to help purchase a new Illumina NovaSeq 6000. Thi …


Cancer Letters: Androgen deprivation-induced elevated nuclear SIRT1 promotes prostate tumor cell survival by reactivation of AR signaling (Chen)

February 19, 2021

Author links open overlay panels high-BoHuanga, D.Thapaa, A.R.Munoza, S.S.Hussaina, X.Yanga, R.G.Bedollaa, P.Osmulskib, M.E.Gaczynskab, Z.Laibg, Yu-ChiaoChiug, Li-JuWanggY.Chendfg, P.Rivasa, C.Shuddea, R.L.Reddickc, H.Miyamotoh, R.Ghoshabf, A.P.Kumarab …


BMC Microbiology: Comparison of rectal swab, glove tip, and participant-collected stool techniques for gut microbiome sampling

January 14, 2021

Meghan I. Short, Robert Hudson, Benjamin D. Besasie, Kelly R. Reveles, Dimpy P. Shah, Susannah Nicholson, Teresa L. Johnson-Pais, Korri Weldon, Zhao Lai, Robin J. Leach, Bernard Fongang & Michael A. Liss Abstract Background Studies of the gut micro …