Greehey CCRI Archives

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Kathryn Crouch (Aune Lab) Among the Winners at the Robert A. Clark Frontiers of Translational Science Research Day

May 21, 2021

  The Robert Clark Frontiers of Translational Science Research Day showcases posters that illustrate completed or ongoing research projects in Translational Science.  This year, due to current gathering restrictions, the event was hosted virtually …


NIH Grant Awarded to Collaborative Team to Eradicate Ewing Sarcoma (Aune)

May 13, 2021

Despite the breakthroughs being made in treating many cancers with less toxic, targeted, and immune-based therapies, Ewing sarcoma’s 40-year-old chemotherapy regimen remains a significant contributor to mortality and long-term cardiovascular complicati …


Pipette Gazette: Trevi Mancilla First Author Publication in PLOS One About The Significance Of Non-Cardiomyocyte Cells (Aune Lab)

September 30, 2020

Trevi Mancilla, a student in the South Texas Medical Scientist Training Program, has published a first-author publication in PLOS ONE. The title is “Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts.” Her mentor is Dr. Greg Aune. …


Cardiovascular Business: Chemotherapy could be damaging children’s heart cells, leading to problems later in life (Aune)

September 30, 2020

Undergoing chemotherapy can have a negative impact on the cells responsible for repairing heart damage, according to a new study published in PLOS One. This may explain why 20% of children treated with anthracyclines go on to experience heart failure l …


Medical Xpress: Childhood Chemo Alters Heart’s Caretaker Cells, Study Finds (Aune Lab)

September 30, 2020

by Will Sansom, UT Health San Antonio Cancer chemotherapy changes the function of cells that repair heart injury, researchers at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) discovered. Twenty percent of children …


PLOS One: Doxorubicin-induced p53 interferes with mitophagy in cardiac fibroblasts (Aune)

September 22, 2020

T. R. Mancilla, L. R. Davis, G. J. Aune  Abstract Anthracyclines are the critical component in a majority of pediatric chemotherapy regimens due to their broad anticancer efficacy. Unfortunately, the vast majority of long-term childhood cancer survivor …


KABB Fox29: SA STRONG: Local doctor beats cancer, now changing lives of young patients (Aune Lab)

August 27, 2020

A UT Health San Antonio doctor who beat cancer is on a mission to help young cancer patients. Dr. Greg Aune, UT Health San Antonio Pediatric Oncologist, is recalling his days as a young athlete. “My sophomore year of high school I was playing a lot of …


Pipette Gazette: Unknown Pathogenic Agents: When Common Decency Is Better Than Nothing (Aune Lab)

April 6, 2020

Originally Published, Pipette Gazette: By: Brian Iskra, The pandemic of COVID-19 is a challenging situation for every member of society; we all have our role to play in mitigating the mortality caused by the infection. Medical professionals are at the …


KLRN: The Gene San Antonio | Dr. Gregory Aune

March 27, 2020

https://www.youtube.com/watch?v=nKvk6YL-MVg     Aune Lab    


bioRxiv : Assessing the Heterogeneity of Cardiac Non-myocytes and the Effect of Cell Culture with Integrative Single Cell Analysis

March 4, 2020

Abstract Cardiac non-myocytes comprise a diverse and crucial cell population in the heart that plays dynamic roles in cardiac wound healing and growth. Non-myocytes broadly fall into four cell types: endothelium, fibroblasts, leukocytes, and pericytes. …