Greehey CCRI Archives
Genes & Cancer: EZH2 suppresses endogenous retroviruses and an interferon response in cancers (Shiio Lab)
January 10, 2022Panneerselvam Jayabal1, Xiuye Ma1 and Yuzuru Shiio1,2,3 ABSTRACT Ewing sarcoma is an aggressive cancer of the bone and soft tissue in children. It is characterized by the chromosomal translocation between EWS and an Ets family transcription factor, mos …
PMC: The Role of Hedgehog Pathway in Uterine Leiomyosarcoma (Houghton Lab)
January 7, 2022Natalia Garcia,1 Mara Ulin,2 Ayman Al-Hendy,3 and Qiwei Yang3 DESCRIPTION The uterine Leiomyosarcoma (LMS) represents 3%-7% of all uterine cancers. This rare tumor has an annual incidence of 0.8 per 100,00 women. Unfortunately, LMS is well known for it …
MDPI: Altertoxin II, a Highly Effective and Specific Compound against Ewing Sarcoma (Houghton Lab)
January 6, 2022Andrew J. Robles Wentao Dai Saikat Haldar Hongyan Ma Victoria M. Anderson Ross D. Overacker April L. Risinger, Sandra Loesgen Peter J. Houghton Robert H. Cichewicz Susan L. Mooberry Simple Summary Ewing sarcoma is a cancer of the bone and soft tissues …
ASM Journals: GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi’s Sarcoma-Associated Herpesvirus-Induced Cellular Transformation (Lai)
January 5, 2022Shan Wei, Songjian Lu, Lifan Liang, Xian Wang, Wan Li, Tingting Li, Luping Chen, , Enguo Ju, Xinquan Zhang, Zhao Lai, Yufei Huang, Xinghua Lu, Shou-Jiang Gao ABSTRACT Infection by Kaposi’s sarcoma-associated herpesvirus (KSHV) is causally associated w …
Briefings in Bioinformatics: Deep learning tackles single-cell analysis—a survey of deep learning for scRNA-seq analysis (Chen Lab)
January 4, 2022Mario Flores, Zhentao Liu, Tinghe Zhang, Md Musaddaqui Hasib, Yu-Chiao Chiu, Zhenqing Ye, Karla Paniagua, Sumin Jo, Jianqiu Zhang, Shou-Jiang Gao, Yu-Fang Jin, Yidong Chen, Yufei Huang Abstract Since its selection as the met …
MDPI: The RNA-Binding Protein Musashi1 Regulates a Network of Cell Cycle Genes in Group 4 Medulloblastoma (Penalva Lab)
December 25, 2021by Mirella Baroni 1 , Gabriela D. A. Guardia 2 , Xiufen Lei 1, Adam Kosti 1,3, Mei Qiao 1, Tesha Landry 1, Karl Mau 1, Pedro A. F. Galante 2 and Luiz O. F. Penalva Abstract Medulloblastoma is the most common malignant brain tumor in children. Treatme …
MSN: Using Next Generation Sequencing, the Greehey CCRI bioinformatics team is helping determine COVID19 strains (Chen, Lai, Zheng, Wang Labs)
December 17, 2021“Since the coronavirus pandemic began almost two years ago there have been over a dozen strains of the virus. Here at UT Health San Antonio, they have a lab which differentiates between each of the strains in an effort to save lives. UT Health San Anto …
Journal of Clinical & Translational Science: Examining access to care in clinical genomic research and medicine: Experiences from the CSER Consortium (Tomlinson)
December 13, 2021Amanda M. Gutierrez Jill O. Robinson, Simon M. Outram, Hadley S. Smith, Stephanie A. Kraft, Katherine E. Donohue, Barbara B. Biesecker, Kyle B. Brothers, Flavia Chen, Benyam Hailu, Lucia A. Hindorff, Hannah Hoban, Rebecca L. Hsu, Sara J. Knight, Barbar …
European Journal of Cancer: Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors: A systematic review and recommendations from the International Late Effects of Childhood Cancer Guideline Harmonization Group
December 6, 2021Elvira C.van Dalena Renée L.Muldera EugeneSuhb Matthew J.Ehrhardtc Gregory J.Auned Bradley J.Bensong JuttaBergler-Kleinh Ming H.Cheni EvaFreyf UlrikeHennewigj LianeLockwoodk UllaMartinssonl MonicaMuracam Helenavan der Pala ChrisPlummern KatrinScheinema …
Childhood Cancer Q&A: David Libich, PhD
December 1, 2021Asst Prof. David S. Libich, PhD,and members of his lab. What are some achievements you’ve made in advancing scientific knowledge relevant to childhood cancer research? My lab works on Ewing sarcoma, specifically on how the EWS-FLI1 oncogenic fusion pro …