Greehey CCRI News & Events Archive

Filter results


 

UT Health SA Newsroom: Zebrafish model explains how recurring cancer may resist treatment

July 21, 2017

UT Health San Antonio researchers are learning how stem cell biology causes 30 percent of children who have a rare muscle cancer to relapse and not respond to treatment. To do this, the lab of Myron Ignatius, Ph.D., at UT Health’s Greehey Children’s Ca …


UT Health SA Newsroom: Surprising finding using zebrafish model explains how recurring cancer may resist treatment

July 21, 2017

SAN ANTONIO (July 21, 2017) ― UT Health San Antonio researchers are learning how stem cell biology causes 30 percent of children who have a rare muscle cancer to relapse and not respond to treatment. To do this, the lab of Myron Ignatius, Ph.D., at UT …


Cancer Knowledge Network: Cancer Childhood ALL: Increased Survival Leads to a Greater Emphasis on Preserving Neurocognitive Function

July 20, 2017

THE RESEARCH: Neurocognitive Functioning of Children Treated for High-Risk B-Acute Lymphoblastic Leukemia Randomly Assigned to Different Methotrexate and Corticosteroid Treatment Strategies: A Report From the Children’s Oncology Group.  As part of a cl …


Clinical Cancer Research: Bioluminescence Imaging Enhances Analysis of Drug Responses in a Patient-Derived Xenograft Model of Pediatric ALL

July 15, 2017

Luke Jones 1, Jennifer Richmond 1, Kathryn Evans 1, Hernan Carol 1, Duohui Jing 1, Raushan T Kurmasheva 2, Catherine A Billups 3, Peter J Houghton 2, Malcolm A Smith 4, Richard B Lock 5 Abstract Purpose: Robust preclinical models of pediatric acute lym …


Cancer Knowledge Network: New Biomarker Predicts Late Neurocognitive Deficits in Adult Survivors of Childhood Leukemia

July 13, 2017

THE RESEARCH: Journal of the National Cancer Institute:  Neurocognitive Sequelae in Adult Childhood Leukemia Survivors Related to Levels of Phosphorylated Tau.  Researchers compared intellectual performance, memory, and executive functioning between 31 …


Cancer Knowledge Network: Neurocognitive Function, Sleep, and Fatigue in Female Childhood ALL Survivors

July 6, 2017

THE RESEARCH: Cancer: Impact of sleep, fatigue, and systemic inflammation on neurocognitive and behavioral outcomes in long-term survivors of childhood acute lymphoblastic leukemia. Researchers at St. Jude Children’s Research Hospital compiled cohorts …


Cancer Knowledge Network: Chemotherapy More Effective at Causing Programmed Cell Death in Young Tissues

June 28, 2017

THE RESEARCH:  Cancer Cell:  Developmental Regulation of Mitochondrial Apoptosis by c-Myc Governs Age- and Tissue-Specific Sensitivity to Cancer Therapeutics.  Programmed cell death or apoptosis has been extensively studied in cancerous tissues and is …


Cancer Knowledge Network: Pregnancy in Female Cancer Survivors: Increased Risks for Mother and Baby

June 21, 2017

Journal of the National Cancer Institute: Pregnancy and Labor Complications in Female Survivors of Childhood Cancer:  The British Childhood Cancer Survivor Study.  Researchers in the United Kingdom compiled data on pregnancy complications including ges …


Cancer Knowledge Network: Decreased Therapy Results in Fewer Second Cancers

June 15, 2017

JAMA:  Temporal Trends in Treatment and Subsequent Neoplasm Risk Among 5-Year Survivors of Childhood Cancer, 1970-2015.  Investigators from the Childhood Cancer Survivor Study (CCSS) used longitudinal cohort data to compile the 15-year cumulative incid …


Cell Report: The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma

June 13, 2017

Myron S Ignatius 1, Madeline N Hayes 2, Riadh Lobbardi 2, Eleanor Y Chen 3, Karin M McCarthy 4, Prethish Sreenivas 5, Zainab Motala 6, Adam D Durbin 7, Aleksey Molodtsov 4, Sophia Reeder 4, Alexander Jin 4, Sivasish Sindiri 8, Brian C Beleyea 9, Deepak …