Greehey CCRI Archives
eLife: tp53 deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish
September 7, 2018Myron S Ignatius, Madeline N Hayes, Finola E Moore, Qin Tang, Sara P Garcia, Patrick R Blackburn, Kunal Baxi, Long Wang, Alexander Jin, Ashwin Ramakrishnan, Sophia Reeder, Yidong Chen, Gunnlaugur Petur Nielsen, Eleanor Y Chen, Robert P Hasserjian, Fran …
JCI Insight: IL-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis
August 23, 2018Amy C. Gross,1 Hakan Cam,1,2 Doris A. Phelps,3 Amanda J. Saraf,2,4 Hemant K. Bid,1,2 Maren Cam,1 Cheryl A. London,5,6 Sarah A. Winget,1 Michael A. Arnold,7,8 Laura Brandolini,9 Xiaokui Mo,10 John M. Hinckley,1,11 Peter J. Houghton,3 and Ryan D. Roberts …
UT Health SA Newsroom: CPRIT awards millions to UT Health San Antonio
August 18, 2018Cancer prevention programs and initiatives to recruit faculty to UT Health San Antonio got a $3.5 million boost from the Cancer Prevention & Research Institute of Texas (CPRIT). The awards, announced Aug. 16, bringing total funding to UT Health San …
Hyundai Hope on Wheels: Dr Greg Aune (video)
August 17, 2018https://www.youtube.com/watch?v=wJhuaEcqhFk&t=28s Aune Lab
UT Health SA Newsroom: UT Health San Antonio physician-researcher contributes to international screening guidelines for rare pediatric cancers
August 2, 2018SAN ANTONIO (Aug. 2, 2017) ―Approximately 10 percent of childhood cancer can be attributed to genetics. While genomic analysis has been used for some time to identify the risk of inherited cancer in adults, scientists are now using genomic analysis to …
CRISPR – Journal: CRISPR-Based Editing Reveals Edge-Specific Effects in Biological Networks
August 1, 2018Yi Li, Chance M. Nowak, Daniel Withers, Alexander Pertsemlidis, Leonidas Bleris Abstract Unraveling the properties of biological networks is central to understanding both normal and disease cellular phenotypes. Networks consist of functional elements ( …
Cancer Letters: miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer
July 28, 2018Xiaojie Yuab, Yiqiang Zhanga, Xiuye Maa, Alexander Pertsemlidisabc Abstract Microtubule-targeting agents (MTAs) are widely used for the treatment of non-small cell lung cancer (NSCLC). The response rate is only ∼25%, mainly attributable to drug resista …
Oncotarget: Increased expression of the thyroid hormone nuclear receptor TRα1 characterizes intestinal tumors with high Wnt activity
July 24, 2018Joel Uchuya-Castillo, Nicolas Aznar, Carla Frau, Pierre Martinez, Clementine Le Nevé, Laetitia Marisa, Luiz OF Penalva, Pierre Laurent-Puig, Alain Puisieux, Jean-Yves Scoazec, Jacques Samarut, Stephane Ansieau, Michelina Plateroti Our previous work dem …
Journal of Clinical Oncology: Cardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention
July 20, 2018Saro H. Armenian, Gregory T. Armstrong, Gregory Aune, Eric J. Chow, Matthew J. Ehrhardt, Bonnie Ky, ABSTRACT Cardiovascular disease (CVD), which includes cardiomyopathy/heart failure, coronary artery disease, stroke, pericardial disease, arrhythmias, …
Cell Report: Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma
July 10, 2018Seçkin Akgül 1, Yinghua Li 2, Siyuan Zheng 3, Marcel Kool 4, Daniel M Treisman 5, Chaoyang Li 2, Yuan Wang 2, Susanne Gröbner 4, Tsuneo Ikenoue 6, Yiping Shen 7, Sandra Camelo-Piragua 8, Gerald Tomasek 9, Sebastian Stark 4, Vinay Guduguntla 9, James F …