Greehey CCRI News & Events Archive

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Journal of Biomolecular Screening: An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme

September 13, 2008

Amy M Wiles 1, Dashnamoorthy Ravi, Selvaraj Bhavani, Alexander J R Bishop Abstract Genome-wide RNA interference (RNAi) screening allows investigation of the role of individual genes in a process of choice. Most RNAi screens identify a large number of g …


Harvard Medical School, DRSC/TRiP Functional Genomics Resources: An Analysis of Normalization Methods for Drosophila RNAi Genomic Screens and Development of a Robust Validation Scheme

September 1, 2008

AMY M. WILES,* DASHNAMOORTHY RAVI,* SELVARAJ BHAVANI, and ALEXANDER J. R. BISHOP Genome-wide RNA interference (RNAi) screening allows investigation of the role of individual genes in a process of choice. Most RNAi screens identify a large number of gen …


Cancer Research: Chromosomal Breakpoints in Primary Colon Cancer Cluster at Sites of Structural Variants in the Genome

March 1, 2008

Jordi Camps, Marian Grade, Quang Tri Nguyen, Patrick Hörmann, Sandra Becker, Amanda B. Hummon, Virginia Rodriguez, Settara Chandrasekharappa, Yidong Chen, Michael J. Difilippantonio, Heinz Becker, B. Michael Ghadimi and Thomas Ried Abstract Genomic abe …


Cancer Research: EpCAM and α-Fetoprotein Expression Defines Novel Prognostic Subtypes of Hepatocellular Carcinoma

March 1, 2008

Taro Yamashita, Marshonna Forgues, Wei Wang, Jin Woo Kim, Qinghai Ye, Huliang Jia, Anuradha Budhu, Krista A. Zanetti, Yidong Chen, Lun-Xiu Qin, Zhao-You Tang, and Xin Wei Wang Abstract The heterogeneous nature of hepatocellular carcinoma (HCC) and the …


Neoplasia: Comparison of Expression Profiles of Metastatic versus Primary Mammary Tumors in MMTV-Wnt-1 and MMTV-Neu Transgenic Mice1

February 1, 2008

Author links open overlay panelShixia Huang*†‡, Yidong Chen§, Katrina Podsypanina Abstract Distant metastases of human breast cancers have been suggested to be more different from each other than from their respective primary tumors, based on expressio …


Cancer Research: Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen

January 1, 2008

Sally A. Amundson, Khanh T. Do, Lisa C. Vinikoor, R. Anthony Lee, Christine A. Koch-Paiz, Jaeyong Ahn, Mark Reimers, Yidong Chen, Dominic A. Scudiero, John N. Weinstein, Jeffrey M. Trent, Michael L. Bittner, Paul S. Meltzer and Albert J. Fornace Jr. …


Molecular Cancer Research: Mouse Embryo Fibroblasts Lacking the Tumor Suppressor Menin Show Altered Expression of Extracellular Matrix Protein Genes

October 1, 2007

Abstract Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized primarily by endocrine tumors of the parathyroids, anterior pituitary, and enteropancreatic endocrine tissues. Affected individuals carr …


Cancer Biology & Therapy: Silencing of lactotransferrin expression by methylation in prostate cancer progression

July 11, 2007

Syed Shaheduzzaman, Anu Vishwanath, Bungo Furusato, Jennifer Cullen, Yongmei Chen, Lionel Bañez, Martin Nau, Lakshmi Ravindranath, Kee-Hong Kim, Ahmed Mohammed, Yidong Chen, Mathias Ehrich, Vasantha Srikantan, Isabell A. Sesterhenn, David G. McLeod, Ma …


Advances in Genetics: Involvement of Homologous Recombination in Carcinogenesis

April 21, 2007

Author links open overlay panelRamuneReliene* Alexander J.R.Bishop §Robert H.Schiestl*†‡ Abstract DNA alterations of every type are associated with the incidence of carcinogenesis, often on the genomic scale. Although homologous recombination (HR) is a …


UT Health SA Newsroom: UTHSC, community celebrate Greehey gift

April 7, 2007

A chain of people – including an adolescent cancer survivor, a medical student, a research fellow, and a physician and scientist – symbolized the impact of The Greehey Family Foundation’s $25 million gift to The University of Texas Health Science Cente …