Greehey CCRI Archives
BMC Genomics: Detection of high variability in gene expression from single-cell RNA-seq profiling
August 22, 2016Hung-I Harry Chen, Yufang Jin, Yufei Huang & Yidong Chen Abstract Background The advancement of the next-generation sequencing technology enables mapping gene expression at the single-cell level, capable of tracking cell heterogeneity and determina …
BMC Genomics: A hierarchical model for clustering m6A methylation peaks in MeRIP-seq data
August 22, 2016Xiaodong Cui, Jia Meng, Shaowu Zhang, Manjeet K. Rao, Yidong Chen & Yufei Huang Abstract Background The recent advent of the state-of-art high throughput sequencing technology, known as Methylated RNA Immunoprecipitation combined with RNA sequencin …
BMC Genomics: CrossLink: a novel method for cross-condition classification of cancer subtypes
August 22, 2016Chifeng Ma, Konduru S. Sastry, Mario Flore, Salah Gehani, Issam Al-Bozom, Yusheng Feng, Erchin Serpedin, Lotfi Chouchane, Yidong Chen & Yufei Huang Abstract Background We considered the prediction of cancer classes (e.g. subtypes) using patient gen …
BMC Genomics: MBDDiff: an R package designed specifically for processing MBDcap-seq datasets
August 18, 2016Yuanhang Liu, Desiree Wilson, Robin J. Leach Yidong Chen Abstract Background Since its initial discovery in 1975, DNA methylation has been intensively studied and shown to be involved in various biological processes, such as development, aging, an …
San Antonio Report: Commentary: Are Questions More Powerful Than Answers?
July 23, 2016In the afternoon, the students had an opportunity to meet with Dr. Alexander Pertsemlidis, associate professor of pediatrics, hematology, and oncology at the Greehey Children’s Cancer Research Institute at the University of Texas Health Science Center. …
San Antonio Business Journal: SA biotech company and Health Science Center to use the power of collaboration to combat cancer
July 13, 2016One of San Antonio’s more promising bioscience companies, bioAffinity Technologies Inc., has locked up a key deal, renewing its collaborative agreement with the University of Texas Health Science Center at San Antonio. The extension will allow the two …
SA Business Journal: Cancer money to boost local pediatric research
July 3, 2016The Cancer Prevention & Research Institute of Texas has awarded nearly $11 million to the University of Texas Health Science Center at San Antonio in its latest funding round. That award includes $5 million to help establish the Texas Pediatric Pat …
American Journal of Botany: Most Compositae (Asteraceae) are descendants of a paleohexaploid and all share a paleotetraploid ancestor with the Calyceraceae
July 1, 2016Michael S Barker 1, Zheng Li 2, Thomas I Kidder 2, Chris R Reardon 2, Zhao Lai 3, Luiz O Oliveira 4, Moira Scascitelli 5, Loren H Rieseberg 6 Abstract Premise of the study: Like many other flowering plants, members of the Compositae (Asteraceae) have a …
Clinical Cancer Research: Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis
July 1, 2016Subapriya Rajamanickam, Subbarayalu Panneerdoss, Aparna Gorthi, Santosh Timilsina, Benjamin Onyeagucha, Dmytro Kovalsky, Dmitri Ivanov, Martha A. Hanes, Ratna K. Vadlamudi, Yidong Chen, Alexander J. Bishop, Jack L. Arbiser and Manjeet K. Rao Abstract P …
Molecular & Cellular Oncology: The inheritance of centromere identity
June 30, 2016Yohei Niikura,Risa Kitagawa & Katsumi Kitagawa ABSTRACT CENP-A (Centromere protein A) is a histone H3 variant that epigenetically determines the centromere position, but the mechanism of its centromere inheritance is obscure. We propose that CENP-A …