Page 88 – Greehey Children's Cancer Research Institute

Nature Methods: Sensitive and specific method for detecting G protein–coupled receptor mRNAs

Published On: November 19, 2006
Shared by Brian Phillips

Arne Hansen, Yidong Chen, Jason M Inman, Quang N Phan, Zhi-Qing Qi, Charlie C Xiang, Miklos Palkovits, Natasha Cherman, Sergei A Kuznetsov, Pamela G Robey, Eva Mezey & Michael J Brownstein Abstract G protein-coupled receptors (GPCRs) mediate the effects of extracellular signaling molecules in all the body’s cells. These receptors are encoded by scarce mRNAs; therefore, detecting their transcripts with conventional microarrays is difficult. We present a […]

The American Journal of Pathology: A Novel Role of Myosin VI in Human Prostate Cancer

Published On: November 1, 2006
Shared by Brian Phillips

Thomas A.Dunn*, Shenglin Chen*, Dennis A.Faith†, Jessica L.Hicks† Elizabeth A.Platz*‡, Yidong Chen§, Charles M.Ewing*, Jurga Sauvageot*, William B.Isaacs*†, Angelo M.De Marzo*†, Jun, Luo* Myosin VI is an actin motor that moves to the minus end of the polarized actin filament, a direction opposite to all other characterized myosins. Using expression microarrays, we identified myosin VI as one of the top […]

Cancer Cell: Prediction of venous metastases, recurrence, and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment

Published On: August 1, 2006
Shared by Brian Phillips

Author links open overlay panelAnuradha Budhu1, Marshonna Forgues1, Qing-HaiYe2, Hu-Liang Jia12, Ping He3, Krista A.Zanetti4, Udai S.Kammula5, Yidong Chen6, Lun-XiuQin2, Zhao-YouTang2, Xin WeiWang1 Summary Hepatocellular carcinoma (HCC) is an aggressive malignancy mainly due to metastases or postsurgical recurrence. We postulate that metastases are influenced by liver microenvironment. Here, we show that a unique inflammation/immune response-related signature is […]

Fertility and Sterility: Identification of molecular markers for endometriosis in blood lymphocytes by using deoxyribonucleic acid microarrays

Published On: June 1, 2006
Shared by Brian Phillips

Idhaliz FloresPhDa Elizabeth RiveraM.Ed.a Spyro MoussesPhDb Yidong ChenPhDc Ester RozenblumPhDd Objective To identify molecular biomarkers for endometriosis in peripheral blood lymphocytes by using DNA microarrays. Design Case-control. Setting Multicenter academic research programs. Patient(s) Premenopausal women with or without endometriosis, determined by obstetrics and gynecology specialists during surgery. Microarray analysis included six endometriosis patients and five controls; 15 endometriosis patients and 15 controls were analyzed […]

Molecular Human Reproduction: Gene expression profiling of human placentas from preeclamptic and normotensive pregnancies

Published On: March 23, 2006
Shared by Brian Phillips

S.R. Hansson, Y. Chen, J. Brodszki, M. Chen, E. Hernandez-Andrade, J.M. Inman, O.A. Kozhich, I. Larsson, K. Marsál, P. Medstrand, C.C. Xiang, M.J. Brownstein Abstract The aim of this study was to investigate patterns of gene expression in placental samples from patients with preeclampsia (PE), persistent bilateral uterine artery notching (without PE), and normal controls. This study included placental tissue from nine women with PE, […]

Oncogene: Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells

Published On: November 13, 2005
Shared by Brian Phillips

M-H Tsai, X Chen, G V R Chandramouli, Y Chen, H Yan, S Zhao, P Keng, H L Liber, C N Coleman, J B Mitchell & E Y Chuang Abstract The p53 protein has been implicated in multiple cellular responses related to DNA damage. Alterations in any of these cellular responses could be related to increased genomic instability. Our previous study has shown that mutations in […]

DNA Repair: p21 controls patterning but not homologous recombination in RPE development

Published On: August 15, 2005
Shared by Brian Phillips

Author links open overlay panelA.J.R.Bishopa B.Kosarasb M.C.Hollanderc A.FornaceJr.c R.L.Sidmanb R.H.Schiestld Abstract p21/WAF1/CIP1/MDA6 is a key cell cycle regulator. Cell cycle regulation is an important part of development, differentiation, DNA repair, and apoptosis. Following DNA damage, p53 dependent expression of p21 results in a rapid cell cycle arrest. p21 also appears to be important for the […]

UT Health SA Newsroom: 400 leaders dedicate Children’s Cancer Research Institute

Published On: March 2, 2004
Shared by Brian Phillips

More than 400 community leaders, elected officials, university regents, and faculty and staff ushered in a new era of South Texas cancer research Feb. 24 at The University of Texas Health Science Center at San Antonio with the dedication of the Children’s Cancer Research Institute (CCRI), a $50 million research facility anchored by the principle […]

UT Health SA Newsroom: Von Eschenbach to help dedicate Children’s Cancer Research Institute

Published On: February 20, 2004
Shared by Brian Phillips

There could be no more fitting keynote speaker, at the dedication of a new cancer research institute for San Antonio, than a three-time cancer survivor. Andrew von Eschenbach, MD, director of the National Cancer Institute, will bring his unique perspective as a cancer physician and survivor to the dedication of The University of Texas Health […]

Von Eschenbach to help dedicate Children’s Cancer Research Institute

Published On: February 20, 2004
Shared by Brian Phillips

Published On: February 20, 2004 Shared by Will Sansom San Antonio (Feb. 20, 2004) – There could be no more fitting keynote speaker, at the dedication of a new cancer research institute for San Antonio, than a three-time cancer survivor. Andrew von Eschenbach, M.D., director of the National Cancer Institute, will bring his unique perspective as […]