EurekAlert: Do all chemotherapies have equal long-term heart risk?

January 21, 2019

SAN ANTONIO — In long-term survivors of childhood cancer, cardiovascular disease is a leading cause of early death from non-cancer causes. In a new study, published Jan. 31 in JAMA Oncology, researchers compared four chemotherapy drugs with the development of cardiomyopathy (abnormal heart muscle with impaired function) years after treatment.


BMC Systems Biology: GSAE: an autoencoder with embedded gene-set nodes for genomics functional characterization

December 21, 2018

Hung-I Harry Chen, Yu-Chiao Chiu, Tinghe Zhang, Songyao Zhang, Yufei Huang & Yidong Chen Abstract Background Bioinformatics tools have been developed to interpret gene expression data at the gene set level, and these gene set-based analyses improve the biologists’ capability to discover the functional relevance of their experiment design. While elucidating gene set individually, inter-gene sets association is rarely taken into […]



University of Texas Health Science Center at San Antonio – UT Health San Antonio, “Non-Hodgkin Lymphoma: David Seitze”

December 12, 2018

UT Health San Antonio MD Anderson Cancer Center’s mission is to conquer cancer through research, prevention, and treatment—while offering world-class care close to home for patients in South Texas. How do ideas, collaboration, and dedication turn into hope for cancer patients? We’re how. You’re why. For more information about UT Health San Antonio, MD Anderson […]


Tiny molecule has big effect in childhood brain tumor studies

December 6, 2018

Sometimes small things make the biggest difference. A new study by UT Health San Antonio researchers found that a molecule thousands of times smaller than a gene are able to kill medulloblastoma, the most common childhood brain cancer.


Science Daily: Tiny molecule has big effect in childhood brain tumor studies

November 7, 2018

Sometimes small things make the biggest difference. A new study by UT Health San Antonio researchers found that a molecule thousands of times smaller than a gene are able to kill medulloblastoma, the most common childhood brain cancer. This tiny molecule, named MiR-584-5p, is quite efficient in its action. MiR-584-5p sensitizes cancer to chemotherapy and […]


European Urology: Metabolic Biosynthesis Pathways Identified from Fecal Microbiome Associated with Prostate Cancer

November 1, 2018

Michael A Liss 1, James Robert White 2, Martin Goros 3, Jonathan Gelfond 3, Robin Leach 4, Teresa Johnson-Pais 4, Zhao Lai 5, Elizabeth Rourke 4, Joseph Basler 4, Donna Ankerst 4, Dimpy P Shah 3 Abstract Background: The fecal microbiome is associated with prostate cancer risk factors (obesity, inflammation) and can metabolize and produce various products that may influence cancer but have yet to be defined in prostate cancer. Objective: To investigate gut bacterial diversity, identify specific […]


Science Advances: Cross-talk among writers, readers, and erasers of m6A regulates cancer growth and progression

October 3, 2018

Subbarayalu Panneerdoss1,2,*, Vijay K. Eedunuri1,2,*, Pooja Yadav1,2, Santosh Timilsina1,2, Subapriya Rajamanickam2,3, Suryavathi Viswanadhapalli4, View ORCID ProfileNourhan Abdelfattah1,2, Benjamin C. Onyeagucha1,2, View ORCID ProfileXiadong Cui5, Zhao Lai2, View ORCID ProfileTabrez A. Mohammad2, View ORCID ProfileYogesh K. Gupta2,6, Tim Hui-Ming uang3, Yufei Huang5,†, View ORCID ProfileYidong Chen2,7,† and View ORCID ProfileManjeet K. Rao1,2,† Abstract The importance of RNA methylation in biological processes is an emerging focus of the investigation. We report that altering […]


Alex’s Lemonade Stand: The Crazy 8 Initiative Topics & Teams

October 1, 2018

ALSF launched the Crazy 8 Initiative to detail roadmaps toward cures for specific, hard-to-treat childhood cancers. This collaborative effort kicked off in the fall of 2018 with a meeting that brought together more than 90 top scientists from around the world providing expertise in eight key areas of need.


YouTube: Children’s Cause, Challenges in Clinical Trial Design

September 18, 2018

CHILDHOOD CANCER HEARING LOSS AN EXTERNALLY-LED PATIENT-FOCUSED DRUG DEVELOPMENT WORKSHOP: CHEMOTHERAPY-INDUCED HEARING LOSS IN PEDIATRIC ONCOLOGY 3:25-3:35 Challenges in Clinical Trial Design in Chemotherapy-Induced Hearing Loss | Greg Aune, MD, PhD, Assistant Professor, UT Health San Antonio-Greehey Children’s Cancer Research Institute The half-day meeting follows the FDA model for externally-led PFDD meetings and will feature […]