Greehey CCRI News & Events Archive

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Cancer Research: RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers

January 1, 2008

Boning Gao 1, Xian-Jin Xie, Chunxian Huang, David S Shames, Tina T-L Chen, Cheryl M Lewis, Aihua Bian, Bifeng Zhang, Olufunmilayo I Olopade, Judy E Garber, David M Euhus, Gail E Tomlinson, John D Minna Abstract The tumor suppressor gene RASSF1A regulat …


Cancer Research: Integrating Global Gene Expression and Radiation Survival Parameters across the 60 Cell Lines of the National Cancer Institute Anticancer Drug Screen

January 1, 2008

Sally A. Amundson, Khanh T. Do, Lisa C. Vinikoor, R. Anthony Lee, Christine A. Koch-Paiz, Jaeyong Ahn, Mark Reimers, Yidong Chen, Dominic A. Scudiero, John N. Weinstein, Jeffrey M. Trent, Michael L. Bittner, Paul S. Meltzer and Albert J. Fornace Jr. …


Clinical Breast Cancer: Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers

December 1, 2007

Tara M Friebel 1, Susan M Domchek, Susan L Neuhausen, Theresa Wagner, D Gareth Evans, Claudine Isaacs, Judy E Garber, Mary B Daly, Rosalind Eeles, Ellen Matloff, Gail Tomlinson, Henry T Lynch, Nadine Tung, Joanne L Blum, Jeffrey Weitzel, Wendy S Rubins …


Molecular Cancer Research: Mouse Embryo Fibroblasts Lacking the Tumor Suppressor Menin Show Altered Expression of Extracellular Matrix Protein Genes

October 1, 2007

Abstract Multiple endocrine neoplasia type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized primarily by endocrine tumors of the parathyroids, anterior pituitary, and enteropancreatic endocrine tissues. Affected individuals carr …


Cancer Biology & Therapy: Silencing of lactotransferrin expression by methylation in prostate cancer progression

July 11, 2007

Syed Shaheduzzaman, Anu Vishwanath, Bungo Furusato, Jennifer Cullen, Yongmei Chen, Lionel Bañez, Martin Nau, Lakshmi Ravindranath, Kee-Hong Kim, Ahmed Mohammed, Yidong Chen, Mathias Ehrich, Vasantha Srikantan, Isabell A. Sesterhenn, David G. McLeod, Ma …


Advances in Genetics: Involvement of Homologous Recombination in Carcinogenesis

April 21, 2007

Author links open overlay panelRamuneReliene* Alexander J.R.Bishop §Robert H.Schiestl*†‡ Abstract DNA alterations of every type are associated with the incidence of carcinogenesis, often on the genomic scale. Although homologous recombination (HR) is a …


Clinical Cancer Research: Gene Expression Profiling Reveals Potential Biomarkers of Human Hepatocellular Carcinoma

February 1, 2007

Hu-Liang Jia, Qing-Hai Ye, Lun-Xiu Qin, Anuradha Budhu, Marshonna Forgues, Yidong Chen, Yin-Kun Liu, Hui-Chuan Sun, Lu Wang, Hong-Zhou Lu, Fang Shen, Zhao-You Tang and Xin Wei Wang Abstract Purpose: Hepatocellular carcinoma (HCC), common cancer worldwi …


Technology in Cancer Research & Treatment: Wnt-1 is Dominant over Neu in Specifying Mammary Tumor Expression Profiles

December 1, 2006

Shixia Huang, PhD*, Katrina Podsypanina, PhD, Yidong Chen, PhD,  Weiyan Cai, Anna Tsimelzon, PhD, Susan Hilsenbeck, PhD, Yi Li, PhD Abstract Wnt-1 and Neu collaborate to induce mammary tumors in bitransgenic mice carrying both MMTV-Wnt-1 and MMTV-Neu. …


Nature Methods: Sensitive and specific method for detecting G protein–coupled receptor mRNAs

November 19, 2006

Arne Hansen, Yidong Chen, Jason M Inman, Quang N Phan, Zhi-Qing Qi, Charlie C Xiang, Miklos Palkovits, Natasha Cherman, Sergei A Kuznetsov, Pamela G Robey, Eva Mezey & Michael J Brownstein Abstract G protein-coupled receptors (GPCRs) mediate the ef …


The American Journal of Pathology: A Novel Role of Myosin VI in Human Prostate Cancer

November 1, 2006

Thomas A.Dunn*, Shenglin Chen*, Dennis A.Faith†, Jessica L.Hicks† Elizabeth A.Platz*‡,  Yidong  Chen§, Charles M.Ewing*, Jurga Sauvageot*, William B.Isaacs*†, Angelo M.De Marzo*†, Jun, Luo* Myosin VI is an actin motor that moves to the minus end of the …


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