Greehey CCRI Archives
Cell Stem Cell: Zika virus targets glioblastoma stem cells through a SOX2-integrin αvβ5 axis
February 6, 2020Zhe Zhu, Pinar Mesci, Jean A Bernatchez, Ryan C Gimple, Xiuxing Wang, Simon T Schafer, Hiromi I Wettersten, Sungjun Beck, Alex E Clark, Qiulian Wu, Briana C Prager, Leo JY Kim, Rekha Dhanwani, Sonia Sharma, Alexandra Garancher, Sara M Weis, Stephen C M …
Adam Kosti Publishes First, First-Author Paper (Penalva Lab)
January 10, 2020ELF4 is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State Abstract 13-Cis-retinoic acid (RA) is typically used in postremission maintenance therapy in patients with neuroblastoma. However, side effects and recurren …
Molecular Cancer Research: ELF4 is a target of miR-124 and promotes neuroblastoma proliferation and undifferentiated state
January 1, 2020Adam Kosti, Liqin Du, Haridha Shivram, Mei Qiao, Suzanne Burns, Juan Gabriel Garcia, Alexander Pertsemlidis, Vishwanath R Iyer, Erzsebet Kokovay, Luiz OF Penalva 13-Cis-retinoic acid (RA) is typically used in postremission maintenance therapy in patien …
Scientific Reports: Genomic analyses of early responses to radiation in glioblastoma reveal new alterations at transcription, splicing, and translation levels
January 1, 2020Choudhary Saket, Suzanne C Burns, Mirsafian Hoda, Wenzheng Li, Dat T Vo, Qiao Mei, Lei Xiufen, Andrew D Smith, Luiz O Penalva High-dose radiation is the main component of glioblastoma therapy. Unfortunately, radio-resistance is a common problem and a m …
bioRxiv: Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches
January 1, 2020Sajina Shakya, Anthony D Gromovsky, James S Hale, Arnon M Knudsen, Briana Prager, Lisa C Wallace, Luiz OF Penalva, Pavlina Ivanova, H Alex Brown, Bjarne W Kristensen, Jeremy N Rich, Justin D Lathia, J Mark Brown, Christopher G Hubert Background: Gliobl …
SCITECH EUROPA: RNA-based Therapeutics for Childhood Cancers
October 21, 2019The mRNA Metabolism in Human Disease: The diverse roles of RNA-binding proteins in glioma development
July 25, 2019Mitzli X. Velasco, Adam Kosti, Luiz O. F. Penalva, Greco Hernández Abstract Post-transcriptional regulation of gene expression is fundamental for all forms of life, as it critically contributes to the composition and quantity of a cell’s proteome. Thes …
RNA: Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development
April 19, 2019Mitzli X Velasco, Adam Kosti, Gabriela DA Guardia, Marcia C Santos, Allison Tegge, Mei Qiao, Bruna RS Correa, Greco Hernández, Erzsebet Kokovay, Pedro AF Galante, Luiz OF Penalva Abstract RNA-binding proteins (RBPs) and miRNAs are critical gene express …
YouTube: Experimental Biology TV, WebsEdgeMedicine
April 4, 2019https://www.youtube.com/watch?v=iWUUaz6A6Mo&t=92s “Cancers in children are rare, and the genetics and epigenetic causes are very different from those of adults. Consequently, the study of the etiology and potential therapies for these tumors requir …
RNA Biology: Luteolin inhibits Musashi1 binding to RNA and disrupts cancer phenotypes in glioblastoma cells
November 18, 2018Caihong Yi,Guiming Li,Dmitri N. Ivanov,Zhonghua Wang,Mitzli X. Velasco,Greco Hernández,Soni Kaundal,Johanna Villarreal,Yogesh K. Gupta ,Mei Qiao,Christopher G. Hubert,Matthew J. Hart &Luiz O.F. Penalva ABSTRACT RNA binding proteins have emerged as …