Greehey CCRI News & Events Archive

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PNAS: Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR

February 26, 2019

Samuel A. Kotler, Vitali Tugarinov, Thomas Schmidt, Alberto Ceccon, David S. Libich, Rodolfo Ghirlando, Charles D. Schwieters, and G. Marius Clore Abstract The N-terminal region of the huntingtin protein, encoded by exon-1, comprises an amphiphilic dom …

San Antonio Business Journal: SA gets small share of more than $90M in state cancer research money

February 22, 2019

The Cancer Prevention and Research Institute of Texas has awarded 54 new academic research, prevention and product development grants totaling nearly $96 million. San Antonio’s cut is $3 million. All three Alamo City grants will support research at UT …

UT Health Newsroom: UT Health San Antonio researchers awarded $3 million for cancer studies

February 22, 2019

Ewing sarcoma research Yuzuru Shiio, M.D., Ph.D., of the Greehey Children’s Cancer Research Institute at UT Health San Antonio, was awarded $1.2 million to further studies of Ewing sarcoma, a pediatric bone and soft tissue cancer. The median age of Ewi …

SA MD News: South Texas Pediatric Blood and Cancer Center: Serving South Texas’ Most Seriously Ill Children Through Cancer Care and Research

February 7, 2019

Expert pediatric cancer physicians and researchers at UT Health San Antonio are working to improve the lives of children with cancer, both for today and tomorrow. UT Health San Antonio, in partnership with the University Health System, offers advanced …

Pharmacy Times: Chemotherapies May Have Varying Long-Term Cardiovascular Risk

February 6, 2019

By studying the outcomes of more than 28,000 long-term childhood cancer survivors in the United States and Europe, researchers found that exposure to different anthracyclines results in variable long-term cardiovascular risk.

BMC Genomics: CeL-ID: cell line identification using RNA-seq data

February 4, 2019

Tabrez A. Mohammad, Yun S. Tsai, Safwa Ameer, Hung-I Harry Chen, Yu-Chiao Chiu & Yidong Chen Abstract Background Cell lines form the cornerstone of cell-based experimentation studies into understanding the underlying mechanisms of normal and diseas …

Journal of Oral Pathology & Medicine: The novel capsazepine analog, CIDD‐99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1‐independent induction of ER stress, mitochondrial dysfunction, and apoptosis

February 3, 2019

Jorge J. De La Chapa, Prajjal K. Singha, Kristen K. Self, McKay L. Sallaway, Stanton F. McHardy, Matthew J. Hart, Howard Stan McGuff, Matthew C. Valdez Francisco Ruiz II, Srikanth R. Polusani, Cara B. Gonzales Abstract Background Oral squamous cell car …

Oncology Learning Network: Podcast – Daunorubicin Decreases Long-Term Cardiomyopathy Risk in Cancer Survivors

January 31, 2019

In an interview with Oncology Learning Network, Gregory J. Aune, MD, Assistant Professor of Pediatrics at UT Health San Antonio and Greehey Children’s Cancer Research Institute, discussed his team’s findings from a multicenter study evaluating the long …

Science Daily: Do all chemotherapies have equal long-term heart risk? (Aune & Tomlinson Labs)

January 31, 2019

In long-term survivors of childhood cancer, cardiovascular disease is a leading cause of early death from non-cancer causes. In a new study, published Jan. 31 in JAMA Oncology, researchers compared four chemotherapy drugs with the development of cardio …

Drug Discovery & Development: Do All Chemotherapies Have Equal Long-Term Heart Risk?

January 31, 2019

Gregory Aune, M.D., Ph.D., of UT Health San Antonio, served on a team that found different chemotherapy drugs used to treat children with cancer appear to have different risks long term for cardiomyopathy (abnormal heart muscle with impaired function). …

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