The Computational Biology and Bioinformatics Initiative (CBBI) offers computational infrastructure, bioinformatics expertise, and interdisciplinary research support to handle and distribute complex datasets. It develops and executes bioinformatics workflows and statistical analyses, with a focus on genomics and systems biology.
The Genome Sequencing Facility (GSF) at Greehey Children’s Cancer Research Institute, UT Health San Antonio, leverages cutting-edge genomic platforms to produce high-quality genomic data and offers comprehensive support for its analysis.
The mission of the TDC is to provide researchers at UT Health San Antonio (UTHSA) and other Texas-based institutes with cutting-edge target identification and validation (TIV) technologies—such as CRISPR screening, gene editing, and drug testing—to advance fundamental cancer biology research and accelerate the discovery of cancer therapeutics.
The Xenograft and Cell Lines Core at Greehey CCRI offers preclinical testing of chemotherapeutics and drug combinations in mouse models. This service is available to the UT Health San Antonio research community, pharmaceutical companies, and any lab interested in conducting animal research.
Histotechnology is the science of preparing tissue samples for microscopic analysis to detect abnormalities and disease-related antigens. Using specialized reagents and staining techniques, histotechnicians apply their knowledge of chemistry and tissue structure to highlight cellular differences, enabling detailed evaluation of protein–antigen interactions.
The biobank contains over 300 models representing a range of pediatric cancer diagnoses available for research. These cryopreserved models are whole-tissue samples developed and passaged in vivo, thereby enhancing their ability to retain the disease characteristics present at the time of biopsy. This process improves the relevance and translational value of the study results for clinical patient care.