iScience: SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics (Aune)

January 19, 2022

Karthik Ramachandran110 Soumya Maity110  Alagar R.Muthukumar2  Soundarya Kandala1  Dhanendra Tomar3  Tarek Mohamed Abd El-Aziz49  Cristel Allen1  Yuyang Sun5  Manigandan Venkatesan1  Travis  R.Madaris1  Kevin Chiem6  RachelTruitt7  Neelanjan Vishnu1  Gregory Aune8 Allen Anderson1 Luis Martinez6  Wenli Yang7  James D.Stockand3  Brij B.Singh5  Subramanya Srikantan1 W. BrianReeves1  Muniswamy Madesh111 Highlights • SARS-CoV-2 perturbs human ion channel, quality control, and [...]

MSN: Using Next Generation Sequencing, the Greehey CCRI bioinformatics team is helping determine COVID19 strains (Chen, Lai, Zheng, Wang Labs)

December 17, 2021

"Since the coronavirus pandemic began almost two years ago there have been over a dozen strains of the virus. Here at UT Health San Antonio, they have a lab which differentiates between each of the strains in an effort to save lives. UT Health San Antonio uses a technology called next-generation sequencing to differentiate the [...]

Yogesh Gupta Awarded, 5-year $3.0 million R01 NIH/NIAID Grant to Support His SARS-CoV-2 and RNA Methylation Work.

July 29, 2021

Dr. Yogesh Gupta was awarded a 5-year $3.0 million R01 NIH/NIAID (National Institute of Allergy and Infectious Diseases) grant to support his SARS-CoV-2 and RNA methylation work. ABSTRACT The massive global pandemic with high morbidity and mortality makes Severe Acute Respiratory Syndrome coronavirus-2  (SARS-CoV-2) one of the deadliest viruses in recent history. It is especially noteworthy for hijacking the normal operations of […]

Texas Public Radio: San Antonio Scientists Uncover One Way The COVID-19 Virus Hides From The Immune System (Gupta)

June 8, 2021

Texas Public Radio | By Bonnie Petrie Published June 7, 2021 at 3:47 PM CDT San Antonio scientists have uncovered one of the disguises used by SARS-CoV-2 — the virus that causes COVID-19 — to hide from the immune system. They are metal ions that everyone has circulating in their body. Dr. Yogesh Gupta is an assistant […]

Texas Standard: We’ve been living with COVID-19 for a long, hard while now. (Gupta + collaborators)

June 7, 2021

Texas Standard Interview: “We’ve been living with COVID-19 for a long, hard while now. But we’re continuing to learn about it: what some Texas researchers say the virus does to hide in your body.”         Click on the image below to hear the interview (Broadcast date 06/7/21, Dr. Gupta appears 14:00-16:20) SOURCE: […]

Nature Communications: Metal ions help COVID-19 virus to disguise itself (Gupta Lab)

June 2, 2021

SAN ANTONIO (June 2, 2021) — Scientists from The University of Texas Health Science Center at San Antonio (Gupta Lab) and other collaborators have discovered a mechanism by which SARS-CoV-2 exploits changes in metal ion concentrations to disguise itself in the body. Varying concentrations of metal ions — positively charged atoms such as magnesium, manganese, […]

Yogesh Gupta,PhD., Invited to Present at Advanced Photon Source of Argonne National Laboratory, COVID-19 Workshop

May 13, 2021

Recently, Greehey CCRI principal investigator, Yogesh Gupta, PhD., was included as an invited speaker with prominent scientists from academia (Ian Wilson, Pamela Bjorkman, and others) and industry (Pfizer and Moderna) at a COVID-19 workshop organized by the Advanced Photon Source of Argonne National Laboratory, Chicago. Broadly, the workshop presented areas where structural biology research, including […]

Dr. Yogesh Gupta Delivers COVID Presentation to International Society for Stem Cell Research

February 26, 2021

    On February 25, 2021, Dr. Yogesh Gupta delivered an invited talk at the International Society for Stem Cell Research COVID network meeting chaired by Hans-Willem Snoeck. MD, PhD (Columbia Univ.) and Todd McDevitt, PhD (Gladstone Inst., UCSF). At this meeting, Dr. Gupta presented his recent research on nonstructural proteins (nsps) of SARS-CoV-2. Some […]

Argonne National Laboratory: Hide and Seek: Understanding How COVID-19 Evades Detection in a Human Cell (Gupta)

November 3, 2020

BY ANDRE SALLES |OCTOBER 29, 2020 Scientists using the Advanced Photon Source have discovered new insights into the ways the SARS-CoV-2 virus camouflages itself inside the human body. Scientists around the world have been working for months to identify and develop treatments that combat SARS-CoV-2, the virus that causes COVID-19. An important part of that process […]

Stand Up to Cancer: Alexander J. R. Bishop, DPhil to Lead One of Three Trans-Atlantic Teams to Study Hard-to-Treat Childhood Cancers

October 20, 2020

Published On: October 19, 2020 Shared by Rosanne Fohn SAN ANTONIO (Oct. 19, 2020) — Although COVID-19 has become the top health and research priority around the world, a child is still diagnosed with cancer every two minutes globally. To meet this urgent need, the Stand Up To Cancer and Cancer Research UK’s Pediatric Cancer New […]