Category
August 16, 2017
“Big Data” is a driving force in cancer research today. Sifting through the data from thousands of cancer genomes will help researchers understand what drives cancer, and help them make predictions about therapies that will be most beneficial to individual patients. To help make sense of these data, and in particular, to apply the findings […]
August 10, 2017
The key to finding a better way to treat a deadly form of childhood cancer may lie in a tiny fish. An unlikely animal model at UT Health San Antonio is helping scientists figure out how to tackle muscle tumors. Inside a fish lab at the Greehey Children’s Cancer Research Institute, rows and rows of glass tanks […]
August 10, 2017
The key to finding a better way to treat a deadly form of childhood cancer may lie in a tiny fish. An unlikely animal model at UT Health San Antonio is helping scientists figure out how to tackle muscle tumors. Inside a fish lab at the Greehey Children’s Cancer Research Institute, rows and rows of glass tanks are […]
August 3, 2017
Pediatric Blood and Cancer: Risk factors and surveillance for reduced bone mineral density in pediatric cancer survivors. Between 2003 and 2010, 475 survivors of childhood leukemia and solid tumors (excluding central nervous system tumors) were screened for decreased bone mineral density (BMD) using dual-energy X-ray absorptiometry (DXA). These screenings were conducted according to the consensus-based Children’s […]
August 1, 2017
Maaged Akiel, Chunqing Guo, Xia Li, Devaraja Rajasekaran, Rachel G. Mendoza, Chadia L. Robertson, Nidhi Jariwala, Fang Yuan, Mark A. Subler, Jolene Windle, Dawn K. Garcia, Zhao Lai, Hung-I Harry Chen, Yidong Chen, Shah Giashuddin, Paul B. Fisher, Xiang-Yang Wang and Devanand Sarkar Abstract Activation of IGF signaling is a major oncogenic event in diverse cancers, including hepatocellular carcinoma (HCC). In this setting, the insulin-like growth factor-binding protein IGFBP7 inhibits IGF signaling by binding the IGF1 receptor (IGF1R), functioning as a candidate tumor suppressor. IGFBP7 abrogates tumors by inhibiting angiogenesis and […]
July 27, 2017
Journal of Clinical Oncology: Endocrine Abnormalities in Aging Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study. Researchers in the United States analyzed the frequency of a range of endocrine disorders reported by 14,290 5-year survivors included in the Childhood Cancer Survivor Study (CCSS). Subjects included in the analysis had a median […]
July 27, 2017
Peter Y. Yu , Heather L. Gardner , Ryan Roberts, Hakan Cam, Seethalakshmi Hariharan, Ling Ren, Amy K. LeBlanc, Hui Xiao, Jiayuh Lin, Denis C. Guttridge, Xiaokui Mo, Chad E. Bennett, Christopher C. Coss, Yonghua Ling, Mitch A. Phelps, Peter Houghton, Cheryl A. London Abstract Background STAT3 is a transcription factor involved in cytokine and receptor kinase […]
July 21, 2017
UT Health San Antonio researchers are learning how stem cell biology causes 30 percent of children who have a rare muscle cancer to relapse and not respond to treatment. To do this, the lab of Myron Ignatius, PhD, at UT Health’s Greehey Children’s Cancer Research Institute, is using zebrafish. These fish have the unusual trait […]
July 21, 2017
SAN ANTONIO (July 21, 2017) ― UT Health San Antonio researchers are learning how stem cell biology causes 30 percent of children who have a rare muscle cancer to relapse and not respond to treatment. To do this, the lab of Myron Ignatius, PhD, at UT Health’s Greehey Children’s Cancer Research Institute, is using zebrafish. These fish […]
July 20, 2017
THE RESEARCH: Neurocognitive Functioning of Children Treated for High-Risk B-Acute Lymphoblastic Leukemia Randomly Assigned to Different Methotrexate and Corticosteroid Treatment Strategies: A Report From the Children’s Oncology Group. As part of a clinical trial for high-risk B-acute lymphoblastic leukemia (B-ALL) conducted by Children’s Oncology Group (COG), U.S. researchers performed neurocognitive evaluations on 192 trial participants that […]